bethanechol

REMS

Postpartum and postoperative nonobstructive urinary retention.
Neurogenic atony of the urinary bladder with retention.

Contraindicated in:

Hypersensitivity;
Mechanical obstruction of the GI or GU tract;
Lactation: Lactation.

Use Cautiously in:

History of asthma;
Ulcer disease;
Cardiovascular disease;
Seizure disorders;
Hyperthyroidism;
Sensitivity to cholinergic agents or effects;
OB: Safety not established in pregnancy;
Pedi: Safety and effectiveness not established in children.

CV: bradycardia, HEART BLOCK, hypotension, SYNCOPE/CARDIAC ARREST

Derm: flushing, sweating

EENT: lacrimation, miosis

GI: abdominal discomfort, diarrhea, nausea, salivation, vomiting

GU: urgency

Neuro: headache, malaise

Resp: bronchospasm

Misc: hypothermia

Drug-drug:

Quinidine and procainamide may antagonize cholinergic effects.
Additive cholinergic effects with cholinesterase inhibitors.
Use with ganglionic blocking agents may result in severe hypotension.
Effectiveness will be ↓ by anticholinergics.

Drug-Natural Products:

Cholinergic effects may be antagonized by angel's trumpet, jimson weed, or scopolia.

(Generic available)

Tablets: 5 mg; 10 mg; 25 mg; 50 mg

PO (Adults ): 25–50 mg 3 times daily. Dose may be determined by administering 5–10 mg every 1–2 hr until response is obtained or total of 50 mg administered or by starting with 10 mg, giving 25 mg 6 hr later, and then, if needed, 50 mg 6 hr later.
PO (Children ): 0.2 mg/kg 3 times daily or 0.15 mg/kg 4 times daily.

~~Urecholine~~

Stimulates cholinergic receptors. Effects include:
- Contraction of the urinary bladder,
- Decreased bladder capacity,
- Increased frequency of ureteral peristaltic waves,

Therapeutic effects:

Bladder emptying.

Therapeutic Classification: urinary tract stimulant

Pharmacologic Classification: cholinergics

Absorption: Poorly absorbed after oral administration.

Distribution: Does not cross the blood-brain barrier.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Duvoid

(response on bladder muscle)

ROUTE	ONSET	PEAK	DURATION
PO	30–90 min	1 hr	6 hr

Explain purpose and side effects of medication. Advise patient to read Patient Information before starting therapy. Instruct to take medication exactly as directed. Missed doses should be taken as soon as possible within 2 hr; otherwise, return to regular dosing schedule. Do not double doses.
Advise patient to notify health care provider of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care provider before taking other medications.
Caution patient to change positions slowly to minimize orthostatic hypotension.
Advise patient to report abdominal discomfort, salivation, sweating, or flushing to health care provider.
Rep: Advise women of reproductive potential to notify health care provider if pregnancy is planned or suspected or if breastfeeding.

be-THAN-e-kole

NDC Code

0832- Upsher-Smith Laboratories, LLC
- 0832-0510- Bethanechol Chloride
  - 0832-0510-00- 100 TABLET in 1 BOTTLE (0832-0510-00)

0832- Upsher-Smith Laboratories, LLC
- 0832-0510- Bethanechol Chloride
  - 0832-0510-01- 100 BLISTER PACK in 1 CARTON (0832-0510-01) / 1 TABLET in 1 BLISTER PACK (0832-0510-89)

0832- Upsher-Smith Laboratories, LLC
- 0832-0510- Bethanechol Chloride
  - 0832-0510-10- 1000 TABLET in 1 BOTTLE (0832-0510-10)

0832- Upsher-Smith Laboratories, LLC
- 0832-0511- Bethanechol Chloride
  - 0832-0511-00- 100 TABLET in 1 BOTTLE (0832-0511-00)

0832- Upsher-Smith Laboratories, LLC
- 0832-0511- Bethanechol Chloride
  - 0832-0511-01- 100 BLISTER PACK in 1 CARTON (0832-0511-01) / 1 TABLET in 1 BLISTER PACK (0832-0511-89)

0832- Upsher-Smith Laboratories, LLC
- 0832-0511- Bethanechol Chloride
  - 0832-0511-10- 1000 TABLET in 1 BOTTLE (0832-0511-10)

0832- Upsher-Smith Laboratories, LLC
- 0832-0511- Bethanechol Chloride
  - 0832-0511-25- 250 TABLET in 1 BOTTLE (0832-0511-25)

0832- Upsher-Smith Laboratories, LLC
- 0832-0512- Bethanechol Chloride
  - 0832-0512-00- 100 TABLET in 1 BOTTLE (0832-0512-00)

0832- Upsher-Smith Laboratories, LLC
- 0832-0512- Bethanechol Chloride
  - 0832-0512-01- 100 BLISTER PACK in 1 CARTON (0832-0512-01) / 1 TABLET in 1 BLISTER PACK (0832-0512-89)

0832- Upsher-Smith Laboratories, LLC
- 0832-0512- Bethanechol Chloride
  - 0832-0512-10- 1000 TABLET in 1 BOTTLE (0832-0512-10)

0832- Upsher-Smith Laboratories, LLC
- 0832-0512- Bethanechol Chloride
  - 0832-0512-25- 250 TABLET in 1 BOTTLE (0832-0512-25)

0832- Upsher-Smith Laboratories, LLC
- 0832-0512- Bethanechol Chloride
  - 0832-0512-50- 500 TABLET in 1 BOTTLE (0832-0512-50)

0832- Upsher-Smith Laboratories, LLC
- 0832-0513- Bethanechol Chloride
  - 0832-0513-00- 100 TABLET in 1 BOTTLE (0832-0513-00)

0832- Upsher-Smith Laboratories, LLC
- 0832-0513- Bethanechol Chloride
  - 0832-0513-01- 100 BLISTER PACK in 1 CARTON (0832-0513-01) / 1 TABLET in 1 BLISTER PACK (0832-0513-89)

0832- Upsher-Smith Laboratories, LLC
- 0832-0513- Bethanechol Chloride
  - 0832-0513-10- 1000 TABLET in 1 BOTTLE (0832-0513-10)

0832- Upsher-Smith Laboratories, LLC
- 0832-0513- Bethanechol Chloride
  - 0832-0513-50- 500 TABLET in 1 BOTTLE (0832-0513-50)

17381- Siegfried Evionnaz SA
- 17381-207-
  - 17381-207-46- 50 kg in 1 DRUM (17381-207-46)

23155- Heritage Pharma Labs Inc. d/b/a Avet Pharmaceuticals Labs Inc.
- 23155-934- Bethanechol Chloride
  - 23155-934-01- 100 TABLET in 1 BOTTLE (23155-934-01)

23155- Heritage Pharma Labs Inc. d/b/a Avet Pharmaceuticals Labs Inc.
- 23155-935- Bethanechol Chloride
  - 23155-935-01- 100 TABLET in 1 BOTTLE (23155-935-01)

23155- Heritage Pharma Labs Inc. d/b/a Avet Pharmaceuticals Labs Inc.
- 23155-936- Bethanechol Chloride
  - 23155-936-01- 100 TABLET in 1 BOTTLE (23155-936-01)

23155- Heritage Pharma Labs Inc. d/b/a Avet Pharmaceuticals Labs Inc.
- 23155-937- Bethanechol Chloride
  - 23155-937-01- 100 TABLET in 1 BOTTLE (23155-937-01)

53746- Amneal Pharmaceuticals of New York LLC
- 53746-571- Bethanechol Chloride
  - 53746-571-01- 100 TABLET in 1 BOTTLE (53746-571-01)

53746- Amneal Pharmaceuticals of New York LLC
- 53746-572- Bethanechol Chloride
  - 53746-572-01- 100 TABLET in 1 BOTTLE (53746-572-01)

53746- Amneal Pharmaceuticals of New York LLC
- 53746-573- Bethanechol Chloride
  - 53746-573-01- 100 TABLET in 1 BOTTLE (53746-573-01)

53746- Amneal Pharmaceuticals of New York LLC
- 53746-574- Bethanechol Chloride
  - 53746-574-01- 100 TABLET in 1 BOTTLE (53746-574-01)

60687- American Health Packaging
- 60687-689- Bethanechol Chloride
  - 60687-689-01- 100 BLISTER PACK in 1 CARTON (60687-689-01) / 1 TABLET in 1 BLISTER PACK (60687-689-11)

60687- American Health Packaging
- 60687-700- Bethanechol Chloride
  - 60687-700-01- 100 BLISTER PACK in 1 CARTON (60687-700-01) / 1 TABLET in 1 BLISTER PACK (60687-700-11)

62135- Chartwell RX, LLC
- 62135-755- Bethanechol Chloride
  - 62135-755-90- 90 TABLET in 1 BOTTLE (62135-755-90)

62135- Chartwell RX, LLC
- 62135-756- Bethanechol Chloride
  - 62135-756-12- 120 TABLET in 1 BOTTLE (62135-756-12)

62135- Chartwell RX, LLC
- 62135-757- Bethanechol Chloride
  - 62135-757-12- 120 TABLET in 1 BOTTLE (62135-757-12)

62135- Chartwell RX, LLC
- 62135-758- Bethanechol Chloride
  - 62135-758-12- 120 TABLET in 1 BOTTLE (62135-758-12)

63629- Bryant Ranch Prepack
- 63629-2022- Bethanechol Chloride
  - 63629-2022-1- 100 TABLET in 1 BOTTLE (63629-2022-1)

63629- Bryant Ranch Prepack
- 63629-2023- Bethanechol Chloride
  - 63629-2023-1- 100 TABLET in 1 BOTTLE (63629-2023-1)

63629- Bryant Ranch Prepack
- 63629-2024- Bethanechol Chloride
  - 63629-2024-1- 100 TABLET in 1 BOTTLE (63629-2024-1)

63629- Bryant Ranch Prepack
- 63629-2025- Bethanechol Chloride
  - 63629-2025-1- 100 TABLET in 1 BOTTLE (63629-2025-1)

65162- Amneal Pharmaceuticals LLC
- 65162-571- Bethanechol Chloride
  - 65162-571-10- 100 TABLET in 1 BOTTLE (65162-571-10)

65162- Amneal Pharmaceuticals LLC
- 65162-571- Bethanechol Chloride
  - 65162-571-11- 1000 TABLET in 1 BOTTLE (65162-571-11)

65162- Amneal Pharmaceuticals LLC
- 65162-571- Bethanechol Chloride
  - 65162-571-50- 500 TABLET in 1 BOTTLE (65162-571-50)

65162- Amneal Pharmaceuticals LLC
- 65162-572- Bethanechol Chloride
  - 65162-572-10- 100 TABLET in 1 BOTTLE (65162-572-10)

65162- Amneal Pharmaceuticals LLC
- 65162-572- Bethanechol Chloride
  - 65162-572-11- 1000 TABLET in 1 BOTTLE (65162-572-11)

65162- Amneal Pharmaceuticals LLC
- 65162-572- Bethanechol Chloride
  - 65162-572-50- 500 TABLET in 1 BOTTLE (65162-572-50)

65162- Amneal Pharmaceuticals LLC
- 65162-573- Bethanechol Chloride
  - 65162-573-10- 100 TABLET in 1 BOTTLE (65162-573-10)

65162- Amneal Pharmaceuticals LLC
- 65162-573- Bethanechol Chloride
  - 65162-573-11- 1000 TABLET in 1 BOTTLE (65162-573-11)

65162- Amneal Pharmaceuticals LLC
- 65162-573- Bethanechol Chloride
  - 65162-573-50- 500 TABLET in 1 BOTTLE (65162-573-50)

65162- Amneal Pharmaceuticals LLC
- 65162-574- Bethanechol Chloride
  - 65162-574-10- 100 TABLET in 1 BOTTLE (65162-574-10)

65162- Amneal Pharmaceuticals LLC
- 65162-574- Bethanechol Chloride
  - 65162-574-50- 500 TABLET in 1 BOTTLE (65162-574-50)

65675- Siegfried St. Vulbas SAS
- 65675-6295-
  - 65675-6295-1- 50 kg in 1 DRUM (65675-6295-1)

65732- Seratec S.A.S.
- 65732-121-
  - 65732-121-01- 1 kg in 1 DRUM (65732-121-01)

73377- AX Pharmaceutical Corp
- 73377-281-
  73377-281-01- 50 g in 1 JAR (73377-281-01)

section name header

Indications ⬇

Contraind./Precautions ⬆ ⬇

Adv. Reactions/Side Effects ⬆ ⬇

Interactions ⬆ ⬇

Availability ⬆ ⬇

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Action ⬆ ⬇

Classifications ⬆ ⬇

Pharmacokinetics ⬆ ⬇

Canadian Brand Names ⬆ ⬇

Time/Action Profile ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

Code ⬆