section name header

Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS)

Interactions ⬆ ⬇

Drug-drug:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Cortrosyn

Action ⬆ ⬇

  • A synthetic form of corticotropin (ACTH); stimulates the adrenal gland to primarily produce corticosteroids (hydrocortisone) and a small amount of mineralocorticoids (aldosterone). Action requires intact adrenal responsiveness.
Therapeutic effects:
  • Production of adrenal steroids after administration.

Classifications ⬆ ⬇

Therapeutic Classification: diagnostic agents, hormones (adrenocorticotropic)

Pharmacologic Classification: hormones

Pharmacokinetics ⬆ ⬇

Absorption: Rapidly absorbed.

Distribution: Well distributed to tissues.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

(effects on plasma cortisol concentrations)

ROUTEONSETPEAKDURATION
IM, IV5 min45–60 minunknown

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

KOE-sin-troe-pin

Code ⬆

NDC Code