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Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

None significant.

Interactions ⬆ ⬇

Drug-drug:

  • None reported.

Availability ⬆ ⬇

(Generic available)
  • Chewable tablets: 40 mgOTC; 80 mgOTC; 125 mgOTC; 150 mgOTC
  • Tablets: 60 mgOTC; 80 mgOTC; 95 mgOTC
  • Capsules: 125 mgOTC; 166 mgOTC; 180 mgOTC; 250 mgOTC
  • Drops: 40 mg/0.6 mLOTC; 40 mg/mLOTC; 95 mg/1.425 mLOTC
  • In combination with:
  • antacidsOTC. See Combination Drugs.

Route/Dosage ⬆ ⬇

  • PO (Adults ): 40–125 mg 4 times daily, after meals and at bedtime (up to 500 mg/day).
  • PO (Children 2–12 yr): 40 mg 4 times daily.
  • PO (Children <2 yr): 20 mg 4 times daily (up to 240 mg/day).

US Brand Names ⬆ ⬇

Degas, Extra Strength Gas-X, Flatulex, Gas-X, Genasyme, Maximum Strength Mylanta Gas, Mylanta Gas, Mylicon, Phazyme

Action ⬆ ⬇

  • Causes the coalescence of gas bubbles.
  • Does not prevent the formation of gas.
Therapeutic effects:
  • Passage of gas through the GI tract by belching or passing flatus.

Classifications ⬆ ⬇

Therapeutic Classification: antiflatulent

Pharmacokinetics ⬆ ⬇

Absorption: No systemic absorption occurs.

Distribution: Not systemically distributed.

Metabolism/Excretion: Excreted unchanged in the feces.

Half-Life: Unknown.

Canadian Brand Names ⬆ ⬇

Gas Relief, Infacol, Ovol, Pediacol

Time/Action Profile ⬆ ⬇

( antiflatulent effect)

ROUTEONSETPEAKDURATION
POimmediateunknown3 hr

Patient/Family Teaching ⬆ ⬇

  • Explain purpose and side effects of medication, and the importance of diet and exercise in gas prevention. Advise patient to read Patient Information before starting therapy.
  • Advise patient to notify health care provider if symptoms persist.
  • Advise patient to notify health care provider of all Rx or OTC medications, vitamins, or herbal products being taken and to consult health care provider before taking other medications.

Pronunciation ⬆ ⬇

si-METH-i-kone

Code ⬆

NDC Code