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Indications ⬇

REMS

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

F and E: hypokalemia (with chronic use)

GI: abdominal cramps, nausea, diarrhea, rectal burning

MS: muscle weakness (with chronic use)

Misc: protein-losing enteropathy, tetany (with chronic use)

Interactions ⬆ ⬇

Drug-drug:

Drug-Food:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Dulcolax, Ex-Lax Ultra

Action ⬆ ⬇

  • Stimulates peristalsis.
  • Alters fluid and electrolyte transport, producing fluid accumulation in the colon.
Therapeutic effects:
  • Evacuation of the colon.

Classifications ⬆ ⬇

Therapeutic Classification: laxatives

Pharmacologic Classification: stimulant laxatives

Pharmacokinetics ⬆ ⬇

Absorption: Variable absorption follows oral administration; rectal absorption is minimal; action is local in the colon.

Distribution: Unknown.

Metabolism/Excretion: Small amounts absorbed are metabolized by the liver.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

( evacuation of bowel)

ROUTEONSETPEAKDURATION
PO6–12 hrunknownunknown
Rectal15–60 minunknownunknown

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

bis-a-KOE-dill

Code ⬆

NDC Code