Treatment of a variety of cutaneous fungal infections, including interdigital tinea pedis (athlete’s foot) (cream and gel), tinea cruris (jock itch) (cream only), and tinea corporis (ringworm) (cream only).
Contraind./Precautions⬆⬇
Contraindicated in:
Hypersensitivity to active ingredients, additives, preservatives, or bases;
Contains alcohol and should be avoided in patients with known intolerance.
Use Cautiously in:
Nail and scalp infections (may require additional systemic therapy);
OB: Safety not established in pregnancy;
Lactation: Safety not established in breastfeeding;
Pedi: Children <12 yr (safety and effectiveness not established for cream for tinea pedis or tinea cruris); children <2 yr (safety and effectiveness not established for cream for tinea corporis).
Adv. Reactions/Side Effects⬆⬇
Local: burning, dryness, itching, local hypersensitivity reactions, redness, stinging
Interactions⬆⬇
Drug-drug:
None reported.
Availability⬆⬇
(Generic available)
Cream: 1%; 2%
Gel: 1%; 2%
Route/Dosage⬆⬇
(Adults ): Interdigital tinea pedis: Apply cream or gel once daily for 2 wk;Tinea cruris or tinea corporis: apply cream once daily for 2 wk.
(Children ≥12 yr): Interdigital tinea pedis: Apply cream or gel once daily for 2 wk.
(Children ≥2 yr): Tinea corporis: Apply cream once daily for 2 wk.
US Brand Names⬆⬇
Naftin
Action⬆⬇
Affects the synthesis of the fungal cell wall.
Therapeutic effects:
Decrease in symptoms of fungal infection.
Classifications⬆⬇
Therapeutic Classification: antifungals (topical)
Pharmacokinetics⬆⬇
Absorption: Absorption through intact skin is minimal.
Distribution: Distribution after topical administration is primarily local.
Metabolism/Excretion: Systemic metabolism and excretion not known following local application.
Half-Life: Not applicable.
Time/Action Profile⬆⬇
ROUTE
ONSET
PEAK
DURATION
Top
unknown
unknown
unknown
Patient/Family Teaching⬆⬇
Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes and vaginal area.
Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream can usually be cleaned by handwashing with soap and warm water.
Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
Advise patient to report increased skin irritation or lack of response to therapy to health care professional.
Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
