miconazole (topical)

Contraindicated in:

Hypersensitivity to active ingredients, additives, preservatives, or bases;
Some products contain alcohol or bisulfites and should be avoided in patients with known intolerance.

Use Cautiously in:

Nail and scalp infections (may require additional systemic therapy);
OB: Safety not established.

Adv. Reactions/Side Effects ⬆ ⬇

Local: burning, itching, local hypersensitivity reactions, redness, stinging

Interactions ⬆ ⬇

Drug-drug:

Not known.

Availability ⬆ ⬇

(Generic available)

Cream: 2%^{Rx, OTC}
Lotion powder: 2%^OTC
Ointment: 2%^OTC
Powder: 2%^OTC
Solution: 2%^OTC
Spray liquid: 2%^OTC
Spray powder: 2%^OTC
Tincture: 2%^OTC
In combination with:
zinc oxide (Vusion)^RxCombination Drugs.

Route/Dosage ⬆ ⬇

(Adults and Children > 2 yr): Apply twice daily. Treat patients with tinea cruris for 2 wk and patients with tinea pedis or tinea corporis for 4 wk.

US Brand Names ⬆ ⬇

Fungoid, Lotrimin AF, Micatin, Zeasorb-AF

Action ⬆ ⬇

Affects the synthesis of the fungal cell wall, allowing leakage of cellular contents.

Therapeutic effects:

Decrease in symptoms of fungal infection.

Classifications ⬆ ⬇

Therapeutic Classification: antifungals (topical)

Pharmacokinetics ⬆ ⬇

Absorption: Absorption through intact skin is minimal.

Distribution: Distribution after topical administration is primarily local.

Metabolism/Excretion: Systemic metabolism and excretion not known following local application.

Half-Life: Not applicable.

Canadian Brand Names ⬆ ⬇

Time/Action Profile ⬆ ⬇

ROUTE	ONSET	PEAK	DURATION
Top	unknown	unknown	unknown

Patient/Family Teaching ⬆ ⬇

Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes.
Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream or lotion can usually be cleaned by handwashing with soap and warm water; stains from ointments can usually be removed with standard cleaning fluids.
Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
Advise patient to report increased skin irritation or lack of response to therapy to health care professional.

Pronunciation ⬆ ⬇

Code ⬆

NDC Code

17337- Olon S.p.A.
- 17337-0529-
  - 17337-0529-0- 1 BAG in 1 DRUM (17337-0529-0) / 1 BAG in 1 BAG / 25 kg in 1 BAG

49452- Spectrum Laboratory Products, Inc.
- 49452-4723-
  - 49452-4723-1- 5 g in 1 BOTTLE, GLASS (49452-4723-1)

49452- Spectrum Laboratory Products, Inc.
- 49452-4723-
  - 49452-4723-2- 25 g in 1 BOTTLE, GLASS (49452-4723-2)

49452- Spectrum Laboratory Products, Inc.
- 49452-4723-
  49452-4723-3- 100 g in 1 BOTTLE, GLASS (49452-4723-3)

49452- Spectrum Laboratory Products, Inc.
- 49452-4723-
  49452-4723-4- 1000 g in 1 BOTTLE, GLASS (49452-4723-4)

51927- Professional Compounding Centers of America dba PCCA
- 51927-0102-
  51927-0102-0- 1 kg in 1 CONTAINER (51927-0102-0)

51927- Professional Compounding Centers of America
- 51927-0311-
  51927-0311-0- 1 kg in 1 BOTTLE (51927-0311-0)

51927- Professional Compounding Centers of America dba PCCA
- 51927-2094-
  51927-2094-0- 1 kg in 1 CONTAINER (51927-2094-0)

61825- Galt Pharmaceuticals, LLC
- 61825-303- Oravig
  61825-303-14- 14 TABLET in 1 BOTTLE (61825-303-14)

67777- Dynarex Corporation
- 67777-316- Dynarex Antifungal Powder
  - 67777-316-02- 24 BOTTLE, PLASTIC in 1 CASE (67777-316-02) / 85 g in 1 BOTTLE, PLASTIC (67777-316-01)

72742- Zen Chemicals Private Limited
- 72742-2500-
  - 72742-2500-2- 10 kg in 1 DRUM (72742-2500-2)

72742- Zen Chemicals Private Limited
- 72742-2500-
  72742-2500-3- 25 kg in 1 DRUM (72742-2500-3)

84722- VIVE HEALTH LLC
- 84722-3057- ANTIFUNGAL
  84722-3057-0- 1 g in 1 JAR (84722-3057-0)

84722- VIVE HEALTH LLC
- 84722-3060- ANTIFUNGAL
  - 84722-3060-0- 1 g in 1 TUBE (84722-3060-0)

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Indications ⬇

Contraind./Precautions ⬆ ⬇