Absorption: Readily absorbed after oral administration.
Distribution: Unknown.
Metabolism/Excretion: Mostly metabolized by the liver; <1% excreted unchanged in urine.
Half-Life: 1.1 hr.
Time/Action Profile⬆⬇
(skeletal muscle effects)
ROUTE
ONSET
PEAK
DURATION
PO
within 1 hr
12 hr
34 hr
Patient/Family Teaching⬆⬇
Explain the purpose and side effects of chlorzoxazone. Instruct patient to take as directed; do not take more than the prescribed amount. Missed doses should be taken within 1 hr of time ordered; otherwise, omit and return to normal dose schedule. Do not double doses. Advise patient to read Patient Information before starting and with each Rx refill in case of changes.
Medication may cause drowsiness and dizziness. Caution patient to avoid driving or other activities requiring alertness until response to drug is known.
Inform patient that drug may discolor urine orange or red.
Instruct patient to notify health care professional if early signs/symptoms of hepatotoxicity (fever, rash, anorexia, nausea, vomiting, fatigue, right upper quadrant pain, dark urine, jaundice); discontinue medication immediately if signs/symptoms occur.
Advise patient to avoid concurrent use of alcohol or other CNS depressants, including opioids with this medication; may cause overdose.
Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and consult health care professional before taking any new medications.
If constipation becomes a problem, advise patient that ↑ fluid intake and bulk in diet and stool softeners may alleviate this condition.
Rep: Advise women of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Pronunciation⬆⬇
klor-ZOX-a-zohn
Code⬆
NDC Code
0254- Endo USA, Inc.
0254-2005- Chlorzoxazone
0254-2005-01- 100 TABLET in 1 BOTTLE (0254-2005-01)
0254- Endo USA, Inc.
0254-2053- Chlorzoxazone
0254-2053-01- 100 TABLET in 1 BOTTLE (0254-2053-01)
0591- Actavis Pharma, Inc.
0591-2520-
0591-2520-00- 14080 TABLET in 1 BOX (0591-2520-00)
0591- Actavis Pharma, Inc.
0591-2520- Chlorzoxazone
0591-2520-01- 100 TABLET in 1 BOTTLE, PLASTIC (0591-2520-01)
0591- Actavis Pharma, Inc.
0591-2520- Chlorzoxazone
0591-2520-05- 500 TABLET in 1 BOTTLE, PLASTIC (0591-2520-05)
0591- Actavis Pharma, Inc.
0591-2520-
0591-2520-77- 16896 TABLET in 1 CONTAINER (0591-2520-77)
16571- Rising Pharma Holdings, Inc.
16571-725- CHLORZOXAZONE
16571-725-01- 100 TABLET in 1 BOTTLE (16571-725-01)
16571- Rising Pharma Holdings, Inc.
16571-725- CHLORZOXAZONE
16571-725-50- 500 TABLET in 1 BOTTLE (16571-725-50)
16571- Rising Pharma Holdings, Inc.
16571-726- CHLORZOXAZONE
16571-726-01- 100 TABLET in 1 BOTTLE (16571-726-01)
16571- Rising Pharma Holdings, Inc.
16571-726- CHLORZOXAZONE
16571-726-50- 500 TABLET in 1 BOTTLE (16571-726-50)
16571- Rising Pharma Holdings, Inc.
16571-727- CHLORZOXAZONE
16571-727-01- 100 TABLET in 1 BOTTLE (16571-727-01)
16571- Rising Pharma Holdings, Inc.
16571-727- CHLORZOXAZONE
16571-727-50- 500 TABLET in 1 BOTTLE (16571-727-50)
24470- Cintex Services, LLC
24470-923- CHLORZOXAZONE
24470-923-10- 100 TABLET in 1 BOTTLE (24470-923-10)
24470- Cintex Services, LLC
24470-923- CHLORZOXAZONE
24470-923-60- 60 TABLET in 1 BOTTLE (24470-923-60)
24470- Cintex Services, LLC
24470-940- CHLORZOXAZONE
24470-940-10- 100 TABLET in 1 BOTTLE (24470-940-10)
24470- Cintex Services, LLC
24470-940- CHLORZOXAZONE
24470-940-50- 500 TABLET in 1 BOTTLE (24470-940-50)
31722- Camber Pharmaceuticals, Inc.
31722-974- CHLORZOXAZONE
31722-974-01- 100 TABLET in 1 BOTTLE (31722-974-01)
31722- Camber Pharmaceuticals, Inc.
31722-974- CHLORZOXAZONE
31722-974-05- 500 TABLET in 1 BOTTLE (31722-974-05)
31722- Camber Pharmaceuticals, Inc.
31722-974- CHLORZOXAZONE
31722-974-10- 1000 TABLET in 1 BOTTLE (31722-974-10)
31722- Camber Pharmaceuticals, Inc.
31722-974- CHLORZOXAZONE
31722-974-30- 30 TABLET in 1 BOTTLE (31722-974-30)
31722- Camber Pharmaceuticals, Inc.
31722-974- CHLORZOXAZONE
31722-974-60- 60 TABLET in 1 BOTTLE (31722-974-60)