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Table 97.2

Focused Assessment in Suspected Acute Gout or Pseudogout

ElementComment
Time course and duration of joint and other symptoms

In gout, attacks begin abruptly, usually overnight, and typically reach maximum intensity within 12 hours.

In pseudogout, attacks may resemble those of acute gout or follow a sub-acute course over several days.

Pattern of joint involvement

In gout, the first MTP joint (podagra) is the initial joint involved in 50% cases and is eventually involved in >90% of cases. Monoarticular involvement occurs commonly, although polyarticular acute flares do occur.

In pseudogout, large joint involvement such as the knee, wrist, elbow or ankle.

Context and comorbiditiesSee Table 97.1.
History of traumaTrauma may cause agitation, with subsequent deposition of urate and CPPD crystals in patients with tophi and chondrocalcinosis, respectively.
Examination of involved joint(s)Swelling, warmth, redness (sometimes resembling cellulitis) and tenderness.
Other signsIn gout, tophi may be present in the helix of the ear, fingers, toes, prepatellar bursa, olecranon bursa.
FeverMay be present in polyarticular presentations of gout or pseudogout (septic arthritis must be excluded).