Adult Dosing
Irritable bowel syndrome (IBS)
- 80 mg/day PO in 4 equally divided doses
- Increase to 160 mg/day PO in 4 equally divided doses depending upon the patient's response during the first week of therapy
Crohn's Disease [Non-FDA approved]
- 20 mg PO q6 hrs, may increase up to 40 mg q6 hrs
Pediatric Dosing
- Safety and effectiveness in pediatric patients have not been established. Dicyclomine is contraindicated in infants less than 6 months of age.
[Outline]
See Supplemental Patient Information
- Heat prostration can occur with dicyclomine use in the presence of a high environmental temperature. If symptoms occur, the drug should be discontinued and supportive measures instituted
- Diarrhea may be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy or colostomy. This drug should not be used in this patient population.
- Therapy may produce drowsiness or blurred vision. Instruct patient not to engage in activities requiring mental alertness, such as operating a motor vehicle or other machinery or performing hazardous work while taking this therapy
- Psychosis, CNS signs and symptoms including confusion, disorientation, short-term memory loss, hallucinations, dysarthria, ataxia, coma, euphoria, decreased anxiety, fatigue, insomnia, agitation and mannerisms, and inappropriate affect have been reported with therapy
- Death and serious respiratory symptoms such as dyspnea, shortness of breath, breathlessness, respiratory collapse, apnea, asphyxia have been reported after administration of dicyclomine syrup to infants
- Seizures, syncope, pulse rate fluctuations, muscular hypotonia, and coma have occurred after administration of dicyclomine syrup to infants. Dicyclomine is contraindicated in infants less than 6 months of age.
- Physician should investigate if any tachycardia before initiating therapy, since it may increase the heart rate. Curare-like action may occur in case of overdosage
Cautions: Use cautiously in:
- Autonomic neuropathy
- Hepatic or renal disease
- Ulcerative colitis
- Hyperthyroidism
- Hypertension
- Coronary heart disease
- Congestive heart failure
- Cardiac tachyarrhythmia
- Hiatal hernia
- Known or suspected prostatic hypertrophy
- High environmental temperature
- History of psychosis
- Elderly patients
Supplemental Patient Information
- In the presence of a high environmental temperature, heat prostration can occur with drug use (fever and heat stroke due to decreased sweating).
- Dicyclomine is contraindicated in infants less than 6 months of age and in nursing mothers.
- Dicyclomine may cause drowsiness or blurred vision. Avoid activities requiring mental alertness or coordination.
Pregnancy Category:B
Breastfeeding: Since dicyclomine has been reported to be excreted in human milk, it is contraindicated in nursing mothers.
Pricing data from www.DrugStore.com in U.S.A.
- Bentyl 10 MG/5ML SYRP [Bottle] (AXCAN PHARMA US)
240 5ml = $35.99
480 5ml = $59.97 - Bentyl 20 MG TABS [Bottle] (AXCAN PHARMA US)
30 mg = $29.99
90 mg = $65.97 - Dicyclomine HCl 10 MG CAPS [Bottle] (MYLAN)
30 mg = $13.99
60 mg = $18.98 - Bentyl 10 MG CAPS [Bottle] (AXCAN PHARMA US)
30 mg = $23.75
90 mg = $53.97 - Dicyclomine HCl 10 MG/5ML SOLN [Bottle] (QUALITEST)
473 5ml = $46.99
1419 5ml = $129.97
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
