Adult Dosing

Scabies

• Massage 5% cream x 1
• 30 gm can be used in average adult
• Leave for 8-14 hours and then should be removed by washing (shower or bath)

Note:

• Repeat in 14 days if live mites present, pruritus may occur after effective treatment

Prevention of head lice/head lice epidemics

• Apply 1% lotion x 1 for 10 minutes
• Repeat application if live lice present 7 days after initial treatment

Pediatric Dosing

• Safety and effectiveness in pediatric patients <2months of age have not been established

Scabies

• Massage 5% cream x 1
• Leave for 8-14 hours and then should be removed by washing (shower or bath)

Note:

• Repeat in 14 days if live mites present, pruritus may occur after effective treatment

Prevention of head lice/head lice epidemics

• Apply 1% lotion x 1 for 10 minutes
• Repeat application if live lice present 7 days after initial treatment

[Outline]

• Adult Dosing
• Pediatric Dosing

• Prevention of scabies (Cream)
• Treatment of head lice and prophylactic use during head lice epidemics (Lotion)

• Hypersensitivity to any of the ingredients of the product
• Hypersensitivity to synthetic pyrethroid or pyrethrin

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

• Discontinue the therapy If hypersensitivity occurs
• Permethrin may worsen pruritus, edema, and erythema and this may be a sign of treatment failure
• Permethrin lotion is for external use only. Eyes should be protected when rinsing hair
• Avoid using lotion near to eyes or mucous membranes as it may cause irritation
• Avoid using lotion in pediatric patients <2 months
• Breathing difficulty and asthamatic episodes may occur with permethrin
• Keep permethrin out of the reach of children. In case of accidental ingestion, contact poison control center

Pregnancy Category:B

Breastfeeding: Avoid use. It is unknown whether if permethrin is excreted in human milk. Manufacturer advises decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

• NEURO: Numbness, tingling
• DERM: Burning, stinging, pruritis, erythema, rash, swelling

• Scabicides, pediculicides; disrupts sodium transport in normal nerve cells, leading to repolarization and paralysis in lice
• Metabolized by liver; CYP450: Unknown
• Excreted in urine
• Half-life: Unknown

US Trade Name(s)

• Elimite
• Nix

US Availability

permethrin (generic)

• CRE: 5%
• OTC LOTN: 1%

Elimite

• CRE: 5%

Nix

• OTC LOTN: 1%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• Lyclear Creme Rinse
• Lyclear Dermal Cream

UK Availability

permethrin (generic)

• CRE: 5%

Lyclear Creme Rinse

• CRE: 1%

Lyclear Dermal Cream

• CRE: 5%

Australian Trade Name(s)

• Lyclear
• Pyrifoam lice breaker
• Quellada head lice treatment
• Quellada scabies treatment

Australian Availability

Lyclear

• CRE: 5%

Pyrifoam lice breaker

• Conditioner: 1%

Quellada head lice treatment

• LIQ: 10 mg/mL

Quellada scabies treatment

• LIQ: 50 mg/mL

[Outline]

Antimicrobials

Dermatologic Topical Agents

Anti-infectives (Other)

Infectious Disease

Dermatologic Topical Agents

Anti-infectives (Other)

Dermatologic

Dermatologic Topical Agents

Anti-infectives (Other)

Pricing data from www.DrugStore.com in U.S.A.

• Permethrin 1 % LOTN [Bottle] (ACTAVIS MID ATLANTIC)
  59 % = $17.99
  118 % = $24.97
• Permethrin 5 % CREA [Tube] (PERRIGO PHARMACEUTICALS)
  60 % = $60.73
  120 % = $97.16

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.