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Use and Dosing

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Hyperlipidemia, Mixed Dyslipidemia, Hypertriglyceridemia, Primary Dysbetalipoproteinemia (Type III hyperlipoprotenemia), slowing the progression of atherosclerosis, and primary prevention of cardiovascular disease

Homozygous Familial hypercholesterolemia

Note: Reserve 40 mg dose for patients who have not achieved LDL-C goal with 20 mg dose

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on CrCl)

Hepatic Dose Adjustment

Warnings/Precautions

Cautions: Use cautiously in

Interactions

Crestor interacts with :

significance_3.gifAcenocoumarol
significance_3.gifCoumadin
significance_2.gifCyclosporine
significance_2.gifEltrombopag
significance_2.gifGemfibrozil
significance_2.gifGengraf
significance_3.gifJantoven
significance_2.gifKaletra
significance_2.gifLopid
significance_2.gifLopinavir
significance_2.gifNeoral
significance_2.gifNorvir
significance_2.gifPromacta
significance_2.gifRestasis
significance_2.gifRifadin
significance_2.gifRifampin
significance_2.gifRimactane
significance_2.gifRitonavir
significance_2.gifSandimmune
significance_3.gifWarfarin

Pregnancy/Breast Feeding

Pregnancy Category:X

Breastfeeding: Since rosuvastatin can cause disruption of infant lipid metabolism, breastfeeding is not recommended. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 12 January 2011). Manufacturer advises that nursing women should not nurse their infants.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

Crestor

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Canadian Trade Name(s)

Canadian Availability

Crestor

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UK Trade Name(s)

UK Availability

Crestor

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Australian Trade Name(s)

Australian Availability

Crestor


[Outline]

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Classification

Endocrine/Metabolic

Antihyperlipidemic Agents
HMG-CoA Reductase Inhibitors (Statins)

Cardiovascular

Antihyperlipidemic Agents
HMG-CoA Reductase Inhibitors (Statins)

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill