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Use and Dosing

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Type II diabetes mellitus (NIDDM)

Fortamet

Glucophage, Riomet, Metformin TABS

Note: Doses >2000 mg may be better tolerated given tid with meals

Glucophage XR, Metformin ETABS

Glumetza

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Type II diabetes mellitus (NIDDM)

10-16 yrs


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Interactions

Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet interacts with :

significance_2.gifAkbeta
significance_2.gifBetagan
significance_2.gifBetapace
significance_2.gifBetapace AF
significance_2.gifBetimol
significance_2.gifBlocadren
significance_2.gifCarteolol
significance_2.gifCarvedilol
significance_2.gifCoreg
significance_2.gifCoreg CR
significance_2.gifCorgard
significance_2.gifHemangeol
significance_2.gifInderal
significance_2.gifInderal LA
significance_2.gifInnopran XL
significance_2.gifIstalol
significance_2.gifLabetalol
significance_2.gifLevatol
significance_2.gifLevobunolol
significance_2.gifNadolol
significance_2.gifOcupress
significance_2.gifPenbutolol
significance_2.gifPindolol
significance_2.gifPropranolol
significance_2.gifSorine
significance_2.gifSotalol
significance_2.gifTimolol
significance_2.gifTimoptic
significance_2.gifTimoptic in ocudose
significance_2.gifTimoptic-XE
significance_2.gifTrandate
significance_2.gifVisken

Pregnancy/Breast Feeding

Pregnancy Category:B

Breastfeeding: Probably safe; metformin is detectable in low levels in the serum of breastfed infants. Milk metformin levels are relatively constant and infants receive <0.5% of the maternal weight-adjusted dosage. Use with caution while nursing newborn/premature infants and those with renal impairment. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 20 April 2011). As per manufacturer data, because of the potential for possible serious adverse reactions in nursing infants a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Adverse Reactions

Clinical Pharmacology

Brands and Availability

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US Trade Name(s)

US Availability

metformin (generic)

Fortamet

Glucophage

Glucophage XR

Glumetza

Riomet

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Canadian Trade Name(s)

Canadian Availability

metformin (generic)

Glucophage

Glumetza

Glycon

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UK Trade Name(s)

UK Availability

metformin (generic)

Glucophage

Glucophage SR

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Australian Trade Name(s)

Australian Availability

metformin (generic)

Diabex, Diaformin, Formet, Glucohexal

Diabex XR

Diaformin XR, Metex XR

Glucomet, Glucophage


[Outline]

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Classification

Endocrine/Metabolic

Diabetic Medications
Biguanides (Metformin)

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill