Adult Dosing

Superficial skin wounds

• Clean the wound and apply small amount on the affected area(s) daily-tid
• May cover the wound with sterile bandage

Pediatric Dosing

Superficial skin wounds

• Clean the wound and apply small amount on the affected area(s) daily-tid
• May cover the wound with sterile bandage

[Outline]

• Adult Dosing
• Pediatric Dosing

• Antiseptic in the management of minor, superficial skin cuts, scrapes and burns

• Hypersensitivity to any of the ingredients of the products
• Large surface area

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Iodine can cause burns on occluded skin, hence do not cover the iodine treated wound with tight bandage
• Do not apply povidone-iodine on a large surface area and for prolong period, to minimize the systemic absorption
• Hypersensitivity reactions like skin irritation can occur with povidone-iodine, discontinue the use if such reactions occurs
• Povidone-iodine can stain the skin and clothes

Cautions: Use cautiously in

• Deep or puncture wounds
• Animal bites
• Serious burns

Supplemental Patient Information

• Advise patients to consult their clinician if condition persists or gets worse

Pregnancy Category:D

Breastfeeding: Use of povidone-iodine in the mother near term and during breastfeeding increases iodine levels in the breastmilk thus causing transient hypothyroidism in breastfed infants, especially in geographic areas that are iodine deficient. Although povidone-iodine is minimally absorbed through intact adult skin, minimize the exposure of nursing mothers to povidone-iodine by using lower concentrations of povidone-iodine, applying it to the smallest possible surface areas, shortening contact time, and avoiding repeated applications. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 17 May 2011).

• DERM: Rash, pruritus, local irritation

• Antiseptic; has broad spectrum bactericidal activity against gram-positive and gram-negative bacteria and also fungicidal, protozoacidal, cysticidal, virucidal, and some sporicidal activity
• Minimal systemic absorption
• Metabolism: Unknown
• Renally excreted
• Half-life: Unknown

US Trade Name(s)

• Only generic available

US Availability

povidone iodine (generic)

• SOLN: 1%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• Betadine Dry Powder Spray
• Betadine Surgical Scrub
• Betadine
• Savlon dry

UK Availability

Betadine Dry Powder Spray

• Aerosol: 2.5% w/w

Betadine Surgical Scrub

• SCRB: 7.5% w/w

Betadine

• OINT: 10%

Savlon dry

• PWDR SPRAY: 1.14% w/w

Australian Trade Name(s)

• Avagard 9240
• Betadine Alcoholic Skin Prep
• Betadine Pre-Operative Body Wash
• Betadine Surgical Scrub
• Evans Dermal Powder (EDP)
• Microshield PVP
• Savlon Antiseptic Powder

Australian Availability

Avagard 9240

• SOLN: 0.75%

Betadine Alcoholic Skin Prep

• SOLN: 30%

Betadine Pre-Operative Body Wash, Microshield PVP

• SOLN: 7.5%

Betadine Surgical Scrub

• SCRB: 7.5%

Evans Dermal Powder (EDP)

• PWDR: 1.4%

Inadine

• DRESSING: 5 x 5 cm
• DRESSING: 9.5 x 9.5 cm

Savlon Antiseptic Powder

• PWDR: 14%

[Outline]

Antimicrobials

Antiseptics

Dermatologic

Dermatologic Topical Agents

Antiseptics