Absorption: Well absorbed following oral administration.
Distribution: Moderate CNS penetration. Crosses the placenta; enters breast milk.
Half-Life: 34 hr.
Contraindicated in:
Use Cautiously in:
CV: HF, ARRHYTHMIAS, BRADYCARDIA, orthostatic hypotension, peripheral vasoconstriction, PULMONARY EDEMA
Derm: itching, rashes
EENT: blurred vision, dry eyes, nasal stuffiness
Endo: hyperglycemia, hypoglycemia
GI: constipation, diarrhea, nausea
GU: erectile dysfunction, ↓libido
MS: arthralgia, back pain, muscle cramps
Neuro: fatigue, weakness, anxiety, depression, dizziness, drowsiness, insomnia, memory loss, mental status changes, nervousness, nightmares, paresthesia
Resp: bronchospasm, wheezing
Misc: drug-induced lupus syndrome
Drug-drug:
Lab Test Considerations: