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Info

Synonym


Tubes

Additional information


Info


Clinical

TestsResultsInterpretation
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Negative
  • Negative
Susceptible
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Positive
  • Positive
Immune due to natural infection
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Negative
  • Positive
Immune due to hepatitis B vaccination
  • HBsAg
  • anti-HBc
  • IgM anti-HBc
  • anti-HBs
  • Positive
  • Positive
  • Positive
  • Negative
Acutely infected
  • HBsAg
  • Core antibody IgG
  • Core antibody IgM
  • Suface antibody
  • Positive
  • Positive
  • Negative
  • Negative
Chronically infected
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Positive
  • Negative
  1. Might be recovering from acute HBV infection
  2. Might be distantly immune and test not sensitive enough to detect very low level of anti-HBs in serum
  3. Might be susceptible with a false positive anti-HBc
  4. Might be undetectable level of HBsAg present in the serum and the person is actually chronically infected

Additional information


Nl Result

Consult your laboratory for their normal ranges as these may vary somewhat from the ones listed below.

Any other results are abnormal and are consistent with either prior, current or chronic infection with hepatitis B (see table below).

TestsResultsInterpretation
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Negative
  • Negative
Susceptible
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Positive
  • Positive
Immune due to natural infection
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Negative
  • Positive
Immune due to hepatitis B vaccination
  • HBsAg
  • anti-HBc
  • IgM anti-HBc
  • anti-HBs
  • Positive
  • Positive
  • Positive
  • Negative
Acutely infected
  • HBsAg
  • Core antibody IgG
  • Core antibody IgM
  • Suface antibody
  • Positive
  • Positive
  • Negative
  • Negative
Chronically infected
  • HBsAg
  • Core antibody
  • Surface antibody
  • Negative
  • Positive
  • Negative
  1. Might be recovering from acute HBV infection
  2. Might be distantly immune and test not sensitive enough to detect very low level of anti-HBs in serum
  3. Might be susceptible with a false positive anti-HBc
  4. Might be undetectable level of HBsAg present in the serum and the person is actually chronically infected

High Result

A high result (e.g. one or more of the markers is positive) must be interpreted within the clinical scenario. Results can be interpreted as follows:

TestsResultsInterpretation
HBsAgNegativeSusceptible
Core antibodyNegative
Surface antibodyNegative
HBsAgNegativeImmune due to natural infection
Core antibodyPositive
Surface antibodyPositive
HBsAgNegativeImmune due to hepatitis B vaccination
Core antibodyNegative
Surface antibodyPositive
HBsAgPositiveAcutely infected
anti-HBcPositive
IgM anti-HBcPositive
anti-HBsNegative
HBsAgPositiveChronically infected
Core antibody IgGPositive
Core antibody IgMNegative
Suface antibodyNegative
HBsAgNegative
  1. Might be recovering from acute HBV infection
  2. Might be distantly immune and test not sensitive enough to detect very low level of anti-HBs in serum
  3. Might be susceptible with a false positive anti-HBc
  4. Might be undetectable level of HBsAg present in the serum and the person is actually chronically infected
Core antibodyPositive
Surface antibodyNegative

Low Result

A low result; or all markers negative is consistent with no prior infection and inadequate response to, or waning immunity to vaccination


References