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Cutaneous reactions are among the most frequent medication toxicities. These can have a wide range of severity and manifestations including urticaria, photosensitivity, erythema multiforme, fixed drug reactions, erythema nodosum, vasculitis, lichenoid reactions, bullous drug reactions, Stevens-Johnson syndrome, and toxic epidermal necrolysis (TEN). Diagnosis is usually made by appearance and careful medication history.

Treatment: Cutaneous Drug Reactions

Withdrawal of the medication. Treatment based on nature and severity of cutaneous pathology.

For a more detailed discussion, see Lawley LP, McCall CO, Lawley TJ: Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders, Chap. 71, p. 344; Shinkai K, Stern RS, Wintroub BU: Cutaneous Drug Reactions, Chap. 74, p. 377; and Bolognia JL, Braverman IM: Skin Manifestations of Internal Disease, Chap. 72, p. 353, in HPIM-19.

Outline

Section 5. Dermatology