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Table 121-2

HEMODYNAMIC COMPLICATIONS IN ACUTE MI

CONDITIONCARDIAC INDEX, (L/min)/m2 PCW, mmHgSYSTOLIC BP, mmHgTREATMENT
Uncomplicated>2.518>100-
Hypovolemia<2.5<15<100

Successive boluses of normal saline

In setting of inferior wall MI, consider RV infarction (esp. if RA pressure >10)

Volume overload>2.5>20>100

Diuretic (e.g., furosemide 10-20 mg IV)

Nitroglycerin, topical paste or IV (Table 121-1 IV VASODILATORS AND INOTROPIC DRUGS USED IN ACUTE MI)

LV failure<2.5>20>100

Diuretic (e.g., furosemide 10-20 mg IV)

IV nitroglycerin (or if hypertensive, use IV nitroprusside)

Severe LV failure<2.5>20<100

If bp 90: IV dobutamine ± IV nitroglycerin or sodium nitroprusside

If bp <90: IV dopamine

If accompanied by pulmonary edema: attempt diuresis with IV furosemide; may be limited by hypotension

If new systolic murmur present, consider acute VSD or mitral regurgitation

Cardiogenic shock<2.2>20<90 with oliguria and confusion

IV norepinephrine or dopamine

Mechanical circulatory support

Reperfusion by PCI or CABG may be life-saving

Abbreviations: CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; PCW, pulmonary capillary wedge pressure; RA, right atrium; VSD, ventricular septal defect.