Definition
Leakage of lens material through an intact lens capsule leads to outflow obstruction (typically in presence of a hypermature cataract).
Unilateral pain, decreased vision (despite poor vision from cataract, increased blurring may be noticeable), tearing, injection, and photophobia.
Critical
Markedly increased IOP, accompanied by iridescent particles and white material in the anterior chamber or on anterior surface of lens capsule. A hypermature (liquefied, Morgagnian) or mature cataract is typical. May occur less commonly in presence of an immature cataract with liquefaction of the posterior cortex. Pain is usually severe.
Other
Microcystic corneal edema, anterior chamber cell and flare (cells may be larger than typical uveitic white blood cells), pseudohypopyon, and severe conjunctival injection. Gonioscopy reveals an open anterior chamber angle. Clumps of macrophages may be seen in the inferior angle.
All of the following can produce an acute increase in IOP to high levels, but none display iridescent particles in the anterior chamber:
Workup
The immediate goal of therapy is to reduce the IOP and inflammation. The cataract should be removed promptly (within several days).