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Symptoms

Irritation and foreign body sensation or may be asymptomatic.

Signs

Critical

Corneal thinning, usually at the limbus, often in the shape of an ellipse, accompanied by an adjacent focal conjunctival or corneal elevation.

Other

Fluorescein pooling in the area but can stain. No infiltrate, no anterior chamber reaction, mild-to-moderate hyperemia.

Differential Diagnosis

See 4.22, Peripheral Corneal Thinning/Ulceration.

Etiology

Poor spread of the tear film over a focal area of cornea (with resultant stromal dehydration) due to an adjacent surface elevation (e.g., chemosis, conjunctival hemorrhage, filtering bleb, pterygium, tumor, and poststrabismus surgery).

Work Up

Workup
  1. History: Previous eye surgery?
  2. Slit lamp examination with fluorescein staining: Look for an adjacent area of elevation.

Treatment

  1. Lubricating or antibiotic ophthalmic ointment every 2 to 4 hours and q.h.s. Temporary patching can be helpful in promoting corneal stromal rehydration in presence of excessive thinning.
  2. Treat the causative elevated lesion according to etiology. Surgical excision may be necessary.
  3. If the cause cannot be removed (e.g., filtering bleb), lubricating ointment should be applied nightly, and viscous artificial tear drops should be used four to eight times per day. If drops are needed more than four times per day, a preservative-free drop should be used.

Follow Up

Unless there is severe thinning, reexamination can be performed in 1 to 7 days, at which time the cornea can be expected to be of normal thickness. If it is not, continue aggressive lubrication.