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Basics

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BASICS

Definition!!navigator!!

Gravitational sedimentation of ingested sand in the large intestine causing colonic impaction and mucosal irritation.

Pathophysiology!!navigator!!

Horses ingest sand while grazing on sandy soil or while eating from the ground in sandy stalls or paddocks. Some horses, particularly foals, develop pica and intentionally eat sand or fine grit contained in decomposed granite used for stall or paddock floors. Ingested sand sediments and accumulates in the large colon until impaction and partial or complete obstruction may occur. As the intestinal contents become dehydrated, the sand may dry out and take on a concrete-like consistency. Fine sand tends to accumulate in the ventral colon, whereas coarse sand or grit may also accumulate in the dorsal and transverse colons. Colonic displacement and/or volvulus is found in up to 54% of horses treated surgically for sand accumulation. The amount of accumulated sand required to induce clinical signs is not known and some horses may tolerate more sand than others. Abdominal pain is caused by colonic distention from the impaction or from ingesta and gas accumulating proximally owing to partial or complete obstruction, and by reflex intestinal spasms stimulated by distention. Chronic irritation of the bowel wall and reduction in the absorptive surface area may interfere with normal water absorption in the colon and give rise to diarrhea.

Systems Affected!!navigator!!

Gastrointestinal system only.

Genetics!!navigator!!

N/A

Incidence/Prevalence!!navigator!!

Worldwide, but more common in geographic locations with sandy soil or where horses are kept in sandy paddocks or stalls and fed on the ground.

Signalment!!navigator!!

No breed or age predilection. Miniature horses may be more predisposed.

Signs!!navigator!!

Historical Findings

Feeding hay and/or grain on the ground or grazing on pastures with sandy soil. Recurrent or chronic colic of mild to moderate severity, intermittent or chronic diarrhea, weight loss, and ill-thrift.

Physical Examination Findings

Colic, scant or absent feces, although watery to “cow pie” diarrhea, may accompany or precede the onset of colic and may be the major presenting sign. Other signs include anorexia, lethargy, depression, abdominal distention, prolonged capillary refill time, and tachypnea. Auscultation of the colon over the most dependent portion of the abdomen for 1–5 min reveals typical “sand sounds” from sand/sand and mucosal/sand friction. Sand sounds are sensitive and reliable indicators of sand accumulation.

In thin horses with massive accumulations of sand in the colon, external palpation and ballottement of the ventral and ventrolateral abdomen may reveal a firm, heavy viscus. Rectal examination usually reveals distinct distention of the large colon and/or cecum, but definitive diagnosis by rectal palpation is achieved in only about 15% of cases. Fecal sand may be detected as a “gritty” feeling during rectal examination and sand may sediment on the floor of the rectum in horses with concomitant diarrhea.

Causes!!navigator!!

See Pathophysiology.

Risk Factors!!navigator!!

See Pathophysiology.

Diagnosis

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DIAGNOSIS

Differential Diagnosis!!navigator!!

  • Large colon impaction, unless a concurrent large colon displacement or torsion is present
  • All other causes of colic, but particularly those that are recurrent, including enterolithiasis, internal abdominal abscess, gastric ulcer, thromboembolic colic, peritonitis, abdominal neoplasia, cholelithiasis, and nephrolithiasis
  • Chronic diarrhea and ill-thrift due to parasitism, inflammatory bowel disease with malabsorption, intestinal neoplasia, and abnormal fermentation associated with noninflammatory bowel disease or antibiotic use

CBC/Biochemistry/Urinalysis!!navigator!!

Nonspecific

Other Laboratory Tests!!navigator!!

  • Feces may contain frank or occult blood
  • Abdominocentesis should be performed with great care so as not to perforate the colon. Abdominal fluid may be normal in horses with sand accumulation, but if the colon is compromised the total protein concentration and white blood cell count may be elevated

Imaging!!navigator!!

  • Abdominal radiography is diagnostic for presence of accumulated sand and serves to monitor the disappearance of sand with medical treatment, particularly in small horses, ponies, and foals. Sand may appear as a homogeneous or granular radiodense accumulation with a horizontal dorsal margin in 1 or more dependent portions of viscera
  • Ultrasonographic evidence is less specific. Signs suggesting sand accumulation include increased contact of the large colon with the ventral abdominal wall, decreased gut motility and hyperechoic acoustic shadowing

Other Diagnostic Procedures!!navigator!!

  • Observation of sand in the feces, abdominal auscultation, rectal palpation, abdominal radiography, abdominal ultrasonography, or sand palpated or obtained during abdominocentesis
  • The sand sedimentation test is performed by breaking up 3 or 4 fecal balls in a rectal sleeve and mixing them with water to form a slurry. The sleeve is suspended to allow the sand to settle inside the fingertips. A sediment of more than 0.6 cm in the fingertips indicates that the horse is passing excessive quantities of sand in feces. In a more quantitative test, the finding of more than a teaspoon (5 g) of sand in the bottom of a bucket after suspending 6 fecal balls with water is considered abnormal
  • Horses with sand impaction may not necessarily have sand in their feces at the time of examination

Pathologic Findings!!navigator!!

N/A

Treatment

Outline


TREATMENT

  • Horses with well-formed impactions or profuse diarrhea benefit from administration of balanced electrolyte solutions intragastrically or IV
  • Analgesia is dictated by the degree of pain
  • Fasting for 24 h or more and intragastric administration of mineral oil and water promotes lubrication and dissolution of the feed impaction
  • Resuspension and removal of sand is best accomplished by intragastric administration of laxatives containing Psyllium hydrophila mucilloid (0.25–0.5 kg/500 kg) in combination with mineral oil and magnesium sulfate (500 g/500 kg horse). Because psyllium gels quickly when mixed with water, it is best administered mixed with 2 L of mineral oil, followed by 4 L of water
  • Daily administration of 0.25–0.5 kg of psyllium orally mixed with grain or sweet feed for mild impactions or administered by nasogastric tube in combination with mineral oil and magnesium sulfate for 10–14 days for severe impactions is recommended

Appropriate Health Care!!navigator!!

  • Initial treatment is handled on an outpatient basis
  • Transportation to a referral center is usually necessary for radiographic confirmation of the diagnosis and surgical management of horses that do not respond to medical therapy

Nursing Care!!navigator!!

Prevention of rolling and self-induced trauma, provision of analgesia, and maintenance of hydration.

Activity!!navigator!!

Horses should be stall-rested and hand-walked until the impaction has resolved.

Diet!!navigator!!

Fasting during medical treatment is needed until the impaction has broken down, feces have been passed, and abdominal pain has abated.

Client Education!!navigator!!

Feeding practices must be modified to prevent further ingestion of sand.

Surgical Considerations!!navigator!!

Affected horses with reduced or absent intestinal motility, with large accumulations of sand, and horses that fail to respond to medical treatment within 48–72 h have uncontrollable pain, abdominal distention, and sudden worsening of clinical signs. Prognosis for long-term survival is favorable if successful evacuation of the colon is achieved and is dependent on concurrent pathology identified at surgery.

Medications

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MEDICATIONS

Drug(s) of Choice!!navigator!!

See Treatment.

Contraindications!!navigator!!

Acepromazine is contraindicated in horses showing evidence of shock.

Precautions!!navigator!!

Repeated use of potent NSAID analgesics to control colic pain should be avoided unless appropriate diagnostic and therapeutic intervention is also pursued.

Possible Interactions!!navigator!!

N/A

Alternative Drugs!!navigator!!

N/A

Follow-up

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FOLLOW-UP

Patient Monitoring!!navigator!!

Repeat physical examinations, sand sedimentation—testing of feces at weekly intervals for 2–4 weeks. Abdominal radiographs to confirm the clearance of sand. Thereafter, abdominal auscultation and sand sedimentation tests should be performed at intervals of 3–6 months.

Prevention/Avoidance!!navigator!!

  • Identification and evacuation of accumulated sand from the large colon and modification of feeding and management practices to minimize further ingestion of significant quantities of sand
  • The source of sand and causes of pica should be identified, horses should not be fed on the ground, and pastures should not be grazed too short. Feeders should be placed above a solid, sand-free surface
  • Horses should receive appropriate quantities of feed, including good quality roughage, on a regular schedule and fresh water should be freely available
  • Avoiding sand as the flooring material for stalls and paddocks may also be necessary
  • Intermittent “purge” treatments with psyllium-containing products is also recommended. Daily oral administration of 0.25 kg of psyllium for 7 consecutive days each month has proved to be effective

Possible Complications!!navigator!!

Include chronic diarrhea, bowel perforation, peritonitis, bowel displacement, with or without strangulation.

Expected Course and Prognosis!!navigator!!

  • Medical therapy is usually successful in resolving sand impaction and relieving signs of colic within 1–4 days. Prognosis is good for sand impactions diagnosed early
  • A guarded prognosis is given in more chronic, high-volume sand impactions which are more likely to require surgical intervention, although survival after surgery is reported to be 75–90%
  • The long-term prognosis depends on preventing sand ingestion and on the degree of mucosal injury and scarring resulting from the original episode

Miscellaneous

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MISCELLANEOUS

Associated Conditions!!navigator!!

Chronic diarrhea, ill-thrift, colonic displacement, colonic rupture, septic peritonitis, endotoxemia, and other postoperative complications listed above have been recognized in association with sand impaction.

Age-Related Factors!!navigator!!

Can occur in horses of any age, including young foals.

Zoonotic Potential!!navigator!!

N/A

Pregnancy/Fertility/Breeding!!navigator!!

Pregnant mares requiring surgical treatment for sand colic are at increased risk for abortion.

Synonyms!!navigator!!

  • Sand colic
  • Sand enteritis
  • Sand enteropathy
  • Sand impaction

Abbreviations!!navigator!!

NSAID = nonsteroidal anti-inflammatory drug

Suggested Reading

Hart KA, Linnenkohl W, Mayer JR, et al. Medical management of sand enteropathy in 62 horses. Equine Vet J 2013;45(4):465469.

Keppie NJ, Rosenstein DS, Holcombe SJ, Schott 2nd HC. Objective radiographic assessment of abdominal sand accumulation in horses. Vet Radiol Ultrasound 2008;49(2):122128.

Author(s)

Authors: Sarah S. le Jeune and W. David Wilson

Consulting Editors: Henry Stämpfli and Olimpo Oliver-Espinosa