The first year of life is characterized by an almost miraculous growth (body weight changes by a factor of three) in size and maturity (Hall SC, Suresh S. Neonatal anesthesia. In: Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Ortega R, Stock MC, eds. Clinical Anesthesia. Philadelphia: Lippincott Williams & Wilkins; 2013:11781215).