Langerhans, Paul
(lang'ĕr-hans‵, lang'ĕr-hanz‵)
Ger. biologist and pathologist, 1847–1888.
L. cell A type of dendritic antigen-presenting cell that typically resides in the skin.
islets of L.Clusters of cells in the pancreas. There are three types: alpha, beta, and delta cells. The alpha cells secrete glucagon, which raises the blood glucose level; the beta cells secrete insulin, which lowers it; and the delta cells secrete somatostatin, an inhibitor of growth hormone secretion. Destruction or impairment of function of the islets of Langerhans may result in diabetes or hypoglycemia. SYN: island s of Langerhans; Langerhans island s; pancreatic island s.