| Cause | Diagnostic clues |
|---|---|
| Appendicitis Acute Appendicitis | Common. The probability of appendicitis can be assessed using the Adult Appendicitis Score (AAS) calculator http://www.appendicitisscore.com/, for example. |
| Intestinal obstruction Obstruction of the Small or Large Bowel, Paralytic Ileus and Pseudo-Obstruction | Small bowel obstruction is most commonly due to adhesions from previous surgical treatment. The most common cause of large bowel obstruction is a tumour. Suspect intestinal ischaemia if the patient is in pain despite a functional nasogastric tube. |
| Intestinal perforation | Several hours to several days from symptom onset Often peritonitis Mere suspicion of intestinal perforation is an indication for starting antimicrobial treatment. Further investigations and treatment immediately |
| Acute cholecystitis Cholelithiasis | The typical symptom is pain starting after a meal in the right upper abdomen that does not subside during follow-up. Abdominal ultrasonography is the first-line investigation if acute cholecystitis is suspected. |
| Acute pancreatitis Acute Pancreatitis | Typically band-like pain predominantly in the left upper abdomen An increased amylase concentration makes the suspected diagnosis more probable. Suspect cholangitis and/or biliary pancreatitis if liver values are increased. If the amylase level is elevated and acute pancreatitis is suspected, CT should preferably be done only after 72-96 hours from the onset of symptoms. |
| Mesenteric ischaemia | The clinical picture may be vague. In patients over 70, triphasic abdominal CT should be performed, including the arterial phase to facilitate a more specific diagnosis. In acute mesenteric ischaemia, further treatment must be provided urgently. |
| Complicated diverticulitis of the colon Diverticulitis and Diverticulosis | The most common site is the sigmoid colon. Perforation may be either restricted, forming an abscess, or spread to cause generalized peritonitis. |
| Volvulus | The most common site is the sigmoid colon, in the left lower abdomen, but volvulus of the caecum is also fairly common. Typically drum-like potbelly |
| Testis torsion Testis Pain | Sore testis tender on palpation particularly in children Explorative surgery should be readily performed. |
| Incarcerated hernia | Rapid repositioning of the hernia is of primary importance. If the hernia can be repositioned and no suspicion of irreversible intestinal ischaemia arises, the patient can usually be discharged. Nevertheless, they should be referred for assessment of need for surgery. See also Hernias in Adults. |
| Cause | Diagnostic clue/example |
|---|---|
| Ectopic pregnancy Ectopic Pregnancy | Pain; referred pain in shoulder. Urine pregnancy test may be negative, rapid serum test is usually positive. |
| Ovarian origin | Ovulation pain, oophoritis, ruptured cyst, torsion of a cyst. |
| Myoma Benign Gynaecological Lesions and Tumours | Torsion; necrosis; bleeding into the abdominal cavity, infection |
| Endometriosis Endometriosis | Menstrual pain |
| Cause | Examples |
|---|---|
| Metabolic disorders | Diabetic ketoacidosis Diabetic Ketoacidosis Porphyria Porphyrias Hypertriglyceridaemia (pancreatitis) Hyperparathyroidism (pancreatitis) Hypercalcaemia and Hyperparathyroidism Uraemia Pain conditions associated with haematological diseases Haemochromatosis Haemochromatosis Addisonian crisis Addison's Disease and other Conditions Inducing Hypocortisolism Mushroom and heavy metal poisonings |
| Infectious causes | Gastroenteritis Acute Diarrhoeal Disease in a Traveller Inflammatory bowel disease (IBD; Crohn's Disease Ulcerative Colitis Hepatitis Viral Hepatitis Perihepatitis Mononucleosis Mononucleosis Herpes zoster Shingles (Herpes Zoster) Pyelonephritis Urinary Tract Infections Prostatitis, epididymitis, orchitis Testis Pain Sepsis Sepsis |
| Referred pain | Myocardial infarction Acute Coronary Syndrome Pericarditis Pericarditis Pneumonia Pneumonia Pleuritis Pleural Effusions and Thoracentesis Pulmonary infarction or embolism Pulmonary Embolism Spontaneous pneumothorax Pneumothorax Heart failure (hepatic stasis) Acute Heart Failure and Pulmonary Oedema Renal calculi Urinary Calculi Haematoma of the rectus abdominis muscle |
| Immunological disorder | Angioneurotic oedema Hereditary Angioedema (HAE) and ACE Inhibitor-Induced Angioedema Polyarteritis nodosa Vasculitides Henoch-Schönlein purpura Henoch-Schönlein Purpura Allergy Eosinophilic gastroenteritis, enteritis or colitis |