Endometriosis - Related Resources

Cochrane reviews

Progestins may be effective in symptomatic treatment of painful endometriosis and provide pain relief similar to danazol and GnRH agonists Progestins for Symptomatic Treatment of Endometriosis.
Danazol appears to be effective in treating the symptoms and signs of endometriosis. However, its use is limited by the occurrence of androgenic side effects Danazol in the Treatment of Endometriosis.
Ovulation suppression is not effective in subfertile women with endometriosis who wish to conceive Ovulation Suppression for Endometriosis.
Hormonal suppression in association with surgery for endometriosis may not provide any significant improvement in clinical outcomes Medical Therapy for Endometriosis Surgery.
Excisional surgery for endometriomata may give more favourable outcomes than drainage and ablation and should be the favoured surgical approach Surgical Techniques for Ovarian Endometriomata.
Hormone replacement therapy for women with endometriosis in post-surgical menopause seems to result in pain and disease recurrence, although the evidence is limited Hormone Therapy for Endometriosis and Surgical Menopause.

CA-125 measurement appears to have a very limited value in the diagnosis of endometriosis

ESHRE guideline for the diagnosis and treatment of endometriosis http://humrep.oxfordjournals.org/cgi/reprint/20/10/2698.pdf
Royal College of Obstetricians and Gynaecologist: The investigation and management of endometriosis http://www.rcog.org.uk

Giudice LC. Clinical practice. Endometriosis. N Engl J Med 2010 Jun 24;362(25):2389-98. [PubMed]
de Ziegler D, Borghese B, Chapron C. Endometriosis and infertility: pathophysiology and management. Lancet 2010 Aug 28;376(9742):730-8. [PubMed]
Farquhar C. Endometriosis. BMJ 2007 Feb 3;334(7587):249-53. [PubMed]
Olive DL. Gonadotropin-releasing hormone agonists for endometriosis. N Engl J Med 2008 Sep 11;359(11):1136-42. [PubMed]
Olive DL, Schwartz LB. Endometriosis. N Engl J Med 1993 Jun 17;328(24):1759-69. [PubMed].

Mahmood TA, Templeton A. Prevalence and genesis of endometriosis. Hum Reprod 1991 Apr;6(4):544-9. [PubMed]
American College of Obstetrics and Gynecology Practice Bulletin: Medical management of endometriosis, 1999
Royal College of Obstetricians and Gynaecologists, Guidelines: The investigations and management of endometriosis, 2000
Kauppila A, Puolakka J, Ylikorkala O. Prostaglandin biosynthesis inhibitors and endometriosis. Prostaglandins 1979 Oct;18(4):655-61. [PubMed]

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