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Information

Editors

MikaRaitanen

Peyronie's Disease (Induratio Penis Plastica)

Definition and aetiology

  • A fibrotic induration of corpus cavernosum
  • The aetiology is unknown; however, some patients (9-39%) have Dupuytren contracture of the palms.

Symptoms and signs

  • The skin is normal and freely mobile at the site of induration.
  • The penis is curved in the direction of the induration during erection. In one third of the patients, the symptoms include erectile pain.
  • In differential diagnosis consider the spread of prostatic carcinoma into the penis (palpate the prostate).
  • Pictures taken by the patient showing the curvature of the penis during erection are very useful when evaluating the symptom.
  • Ultrasound imaging is usually not beneficial.

Treatment

References

  • Russo GI, Milenkovic U, Hellstrom W et al. Clinical Efficacy of Injection and Mechanical Therapy for Peyronie's Disease: A Systematic Review of the Literature. Eur Urol 2018;74(6):767-781. [PubMed]