Erythrocyte defects |
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Cell membrane defects |
Enzymopathies- Haemoglobin abnormalities
- Thalassaemias
- Haemoglobinopathies
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Paroxysmal nocturnal haemoglobinuria (PNH) |
External causes |
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Immunohaemolysis- Autoimmune haemolysis
- Cold haemagglutination syndrome
- Drug-induced immunohaemolysis
- Transfusion reaction
- Mother-child immunisation
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Fragmentation haemolysis- Prosthetic valves, other prostheses, haemoperfusion
- March haemoglobinuria
- Vasculitis
- Disseminated intravascular coagulation (DIC)
- Thrombotic thrombocytopenic purpura (TTP)
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Other external causes- Infections, toxins, burns, hypersplenism
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