Diagnosis and Treatment of Childhood Asthma - Related Resources

Cochrane reviews

Long acting beta2-agonists (LABA) appear to be associated with more serious adverse events than placebo in children with asthma. Combination of corticosteroids to LABA appears to reduce adverse events Safety of Regular Formoterol or Salmeterol in Children with Asthma.
Supplementation of diet with marine n-3 fatty acids seems not to improve asthma symptoms, although the evidence is insufficient Dietary Marine Fatty Acids (Fish Oil) for Asthma in Adults and Children.
Nedocromil sodium used before exercise reduces the severity and duration of exercise-induced bronchoconstriction Nedocromil Sodium for Preventing Exercise-Induced Bronchoconstriction.
Anticholinergic drugs may not be effective in the treatment of chronic asthma in children over two years of age Anticholinergic Therapy for Chronic Asthma in Children over Two Years of Age.
Ketotifen alone or in combination with other interventions appears to improve control of asthma and wheezing in children with mild and moderate asthma, with sedation and weight gain as minor side effects Ketotifen for Asthma in Children.
There is no evidence on the role of psychological interventions for children with asthma Psychotherapeutic Interventions for Children with Asthma.
Family therapy may have some limited effect in asthma management in children Family Therapy for Chronic Asthma in Children.
Bronchodilators to treat infants with bronchiolitis may not improve oxygen saturation, reduce hospital admission after outpatient treatment, or shorten the duration of hospitalization compared to placeboBronchodilators for Bronchiolitis.
There may not be a difference between commercial versus home-made spacers for delivering bronchodilator therapy to children with acute asthma or lower airways obstruction attacks Commercial Versus Home-Made Spacers in Delivering Bronchodilator Therapy for Acute Therapy in Children.
Nedocromil may be effective for improving lung function and symptom scores in children with chronic asthma Nedocromil Sodium for Chronic Asthma in Children.
Multifaceted interventions, characterised by dietary allergen reduction and environmental remediation, may reduce the odds of a physician diagnosis of asthma later in childhood Allergen Reduction Interventions for Preventing Asthma in Children at High Risk..

Clinical guidelines

Managing asthma long term in children 0-4 years of age and 5-11 years of age. In: National Asthma Education and Prevention Program (NAEPP). Expert panel report 3: guidelines for the diagnosis and management of asthma. Bethesda (MD): National Heart, Lung, and Blood Institute; 2007 Aug. p. 281-325 http://www.guideline.gov/summary/summary.aspx?doc_id=11675

Literature

Townshend J, Hails S, Mckean M. Management of asthma in children. BMJ 2007;335:253-257
Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 1995 Jan 19;332(3):133-8. [PubMed]
Säynäjäkangas O, Valmari P, Tuuponen T, Keistinen T. Trends in hospitalization for childhood asthma in Finland in 1996-2004. Acta Paediatr 2007 Jun;96(6):919-23. [PubMed]
Cole A. New cases of asthma in children in England and Wales has fallen by two thirds. BMJ 2005;330:691 http://www.bmj.com/cgi/content/full/330/7493/691-c

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Diagnosis and Treatment of Childhood Asthma - Related Resources

Cochrane reviews

Clinical guidelines

Literature