section name header

Indications

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS


Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: hypotension (high dose), palpitations

Derm: rash

GI: nausea

Neuro: agitation, dizziness, fatigue, headache, sedation (high dose), sleeplessness, sweating, vertigo

Interactions

Natural-Drug Products:

Natural-Natural Products:

Availability

(Generic available)

Route/Dosage

US Brand Names

aubepine, crataegi folium, cum flore, hagedorn, maybush, whitehorn

Action

  • Active compounds in hawthorn include flavonoids and procyanidins.
  • Increase coronary blood flow.
  • Positive inotropic and chronotropic effects because of increased permeability to calcium and inhibition of phosphodiesterase.
Therapeutic effects:
  • Increased cardiac output.
  • Decreased BP, myocardial workload, and oxygen consumption.

Classifications

Therapeutic Classification: antihypertensives, inotropics

Pharmacokinetics

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile

ROUTEONSETPEAKDURATION
POunknown6–8 wkunknown

Patient/Family Teaching

Pronunciation

HAW-thorn