botulism immune globulin

REMS

Contraindicated in:

Use Cautiously in:

Pre-existing renal impairment, diabetes mellitus, volume depletion, sepsis, paraproteinemia, concurrent nephrotoxic agents (↑ risk of adverse renal reactions; use lowest concentration and slowest infusion rate).

Derm: rash

Misc: infusion reactions

Drug-drug:

May interfere with immune response to live-virus vaccines; defer for at least 5 mo.

BabyBIG

Therapeutic effects:

Therapeutic Classification: vaccines/immunizing agents

Pharmacologic Classification: immune globulins

Absorption: IV administration results in complete bioavailabilty.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: 28 days (infants).

(presence of neutralizing antibodies)

ROUTE	ONSET	PEAK	DURATION
IV	rapid	end of instion	up to 6 mos

Inform parents of purpose of medication.
Caution parents to avoid live vaccinations shortly before or within 5 mo of administration.

BOtyoo-lism im-YOON GLOB-yoo-lin