37. Which side effect(s) from the combination therapy of isoniazid and rifampin should a client report immediately?
37. Which side effect(s) from the combination therapy of isoniazid and rifampin should a client report immediately?
. Paleness of conjunctiva and oral mucosa.
. Dark urine and pale-colored stool.
. Blood in the urine.
. Decrease in hearing ability.
Test-Taking Tip
Recognize expected outcomes of therapy, including serious side effects.
Content Area: Adult Health, Infectious Disease; Integrated Process: Nursing Process, Assessment; Cognitive Level: Application; Client Need/Subneed: Physiological Integrity/Pharmacological and Parenteral Therapies/Adverse Effects/Contraindications/Interactions
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Answer 1 is incorrect because these symptoms would be indicative of anemia. Answer 2 is correct because antifungal agents can cause liver damage, which results in obvious jaundice and the disruption of normal bile flow. Answer 3 is incorrect because blood in the urine would indicate a bladder or kidney problem, which is not a side effect of these drugs. Answer 4 is incorrect because ototoxicity more often occurs from other antituberculosis drugs in the aminoglycoside classification (e.g., streptomycin), although ototoxicity can occur from isoniazid or rifampin.