38. A child is admitted for suspicion of Reye syndrome. A nurse understands that symptoms of Reye syndrome follow a timeline. Which manifestations support the nurse's suspicion? Select all that apply.
. Behavioral changes and agitation.
. Administration of acetaminophen.
Test-Taking Tip
When answering this question, categorize symptoms as early or late, and then break it down further by looking at which symptom precedes another.
Content Area: Child Health, Neurological; Integrated Process: Nursing Process, Analysis; Cognitive Level: Analysis; Client Need/Subneed: Physiological Integrity/Physiological Adaptation/Pathophysiology
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Answer 1 is correct because often the first symptoms are behavioral changes such as lethargy, confusion, and combativeness. Answer 2 is incorrect because the administration of acetylsalicylic acid (aspirin) during viral illness, not acetaminophen (Tylenol), is associated with Reye syndrome. Answer 3 is correct because coma is a late symptom of Reye syndrome. Answer 4 is incorrect because the child with Reye syndrome is likely to experience elevated partial thromboplastin time (PTT) as a result of liver damage. Answer 5 is incorrect because intracranial pressure increases during Reye syndrome. Answer 6 is correct because the syndrome does not occur unless the child first has a viral illness.