DDx ⬇
Arthritis
- Cellulitis
- Septic arthritis
- Pseudogout
- Rheumatoid arthritis
- Reactive arthritis (Reiters syndrome)
- Osteoarthritis
- Chronic lead poisoning (saturnine gout)
- Palindromic rheumatism
Podagra
- Trauma
- Cellulitis
- Sarcoidosis
- Pseudogout
- Psoriatic arthritis
- Bursitis of first metatarsophalangeal (MTP) joint (inflamed bunion)
Tophi
- Rheumatoid nodules
- Erythema nodosum
- Gout
- Coccidioidomycosis
- Endocarditis (Oslers nodes)
- Sarcoidosis
- Polyarteritis nodosa
Outline
Related DDx ⬆ ⬇
Etiology ⬆
- Primary, especially Pacific islanders
- Secondary (acquired hyperuricemia):
- Drugs, eg, alcohol, diuretics, low-dose aspirin, niacin, cyclosporine
- Myeloproliferative disease, multiple myeloma, hemoglobinopathy, chronic renal disease, hypothyroidism, psoriasis, sarcoidosis, lead poisoning