PRI-mi-done 
Absorption: 80–100% absorbed from the GI tract when administered orally.
Distribution: Widely distributed. Crosses the placenta and enters breast milk.
Metabolism/Excretion: Converted to phenobarbital and another active anticonvulsant compound (PEMA) by the liver.
Half-life: 3–7 hr.
Contraindicated in:
Use Cautiously in:
CNS: SUICIDAL THOUGHTS, ataxia, drowsiness, vertigo, excitement (↑ in children).
EENT: visual changes.
Resp: dyspnea.
CV: edema, orthostatic hypotension.
GI: anorexia, drug-induced hepatitis, nausea, vomiting.
Derm: alopecia, rash.
Hemat: blood dyscrasias, megaloblastic anemia.
Misc: folic acid deficiency.
Drug-Drug:
Drug-Natural Products:
Drug-Food:
NDC Code*