za-LEP-lon 
Absorption: Rapidly absorbed following oral administration.
Distribution: Well distributed to tissues.
Metabolism/Excretion: Extensively metabolized in the liver (mostly by aldehyde oxidase and some by the CYP3A4 isoenzyme).
Half-life: 1 hr.
Contraindicated in:
Use Cautiously in:
CV: peripheral edema.
Derm: photosensitivity.
EENT: abnormal vision, altered sense of smell, ear pain, epistaxis, hearing sensitivity, ocular pain.
GI: abdominal pain, anorexia, colitis, dyspepsia, nausea.
GU: dysmenorrhea.
Neuro: abnormal thinking, amnesia, anxiety, behavior changes, COMPLEX SLEEP BEHAVIORS (INCLUDING SLEEP DRIVING, SLEEP WALKING, OR ENGAGING IN OTHER ACTIVITIES WHILE SLEEPING), depersonalization, dizziness, drowsiness, hallucinations, headache, hyperesthesia, impaired memory (briefly following dose), impaired psychomotor function (briefly following dose), malaise, nightmares, paresthesia, tremor, vertigo, weakness.
Misc: fever.
Drug-Drug:
Drug-Natural Products:
Drug-Food:
Hepatic Impairment
NDC Code*