tye-ZAN-i-deen
Therapeutic Classification: antispasticity agents (centrally acting)
Pharmacologic Classification: adrenergics
REMS
Absorption: Completely absorbed after oral administration but rapidly metabolized, resulting in 40% bioavailability.
Distribution: Widely distributed.
Half-Life: 2.5 hr.
Contraindicated in:
Use Cautiously in:
EENT: blurred vision, pharyngitis, rhinitis
CV: hypotension, bradycardia
GI: abdominal pain, diarrhea, dry mouth, dyspepsia, constipation, hepatocellular injury, ↑liver enzymes, vomiting
GU: urinary frequency
Derm: rash, skin ulcers, sweating
MS: back pain, myasthenia, paresthesia
Misc: fever, speech disorder
Drug-drug:
Tablets are not interchangeable with capsules
Generic
2 mg
35.39
100
4 mg
47.93
100
2 mg; 4 mgGeneric
2 mg
406.72
150
4 mg
515.53
150
6 mg
773.24
150
2 mg; 4 mg; 6 mgLab Test Considerations:
NDC Code