roe-kyoor-OWN-ee-um
High Alert
Absorption: Following IV administration, absorption is essentially complete.
Distribution: Rapidly distributes into extracellular space.
Half-Life: Infants 3–12 mo: 0.8–1.8 hr; Children 1–3 yr: 0.4–1.8 hr; Children 3–8 yr: 0.5–1.1 hr; Adults: 1.4–2.4 hr (↑ to 4.3 hr in hepatic impairment and 2.4 hr in renal impairment)
| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| IV | 1 min | 0.5–1 min (peds) 1–3.7 min (adults) | 26–40 min (peds) 31 min (adults)* |
*Following 0.6 mg/kg dose in adult patients.
Contraindicated in:
Use Cautiously in:
Drug-drug:
Toxicity and Overdose:
Unplanned administration of a neuromuscular blocking agent instead of administration of the intended medication or administration of a neuromuscular blocking agent in the absence of ventilatory support has resulted in serious harm and death. Confusing similarities in packaging and insufficiently controlled access to these medications are often implicated in these medication errors.
IV Administration:
NDC Code