Therapeutic Classification: antidepressants
Pharmacologic Classification: selective serotonin reuptake inhibitors ssris
BEERS REMS
Absorption: Well absorbed after oral administration.
Distribution: Crosses the blood-brain barrier.
Protein Binding: 94.5%.
Half-Life: 13 days (norfluoxetine 57 days).
Contraindicated in:
Use Cautiously in:
CV: chest pain, palpitations, QT interval prolongation, TORSADES DE POINTES
Derm: ↑sweating, pruritus, erythema nodosum, flushing, rash
EENT: mydriasis, stuffy nose, visual disturbances
Endo: SIADH, dysmenorrhea, hot flush
F and E: hyponatremia
GI: diarrhea, abdominal pain, abnormal taste, anorexia, constipation, dry mouth, dyspepsia, nausea, vomiting, weight loss
GU: ↓libido, delayed/absent orgasm, ejaculatory delay/failure, erectile dysfunction, urinary frequency
Hemat: BLEEDING
MS: arthralgia, back pain, myalgia
Neuro: anxiety, drowsiness, headache, insomnia, nervousness, tremor, abnormal dreams, dizziness, fatigue, hypomania, mania, NEUROLEPTIC MALIGNANT SYNDROME, SEIZURES, SUICIDAL THOUGHTS, weakness
Resp: cough
Misc: fever, flu-like syndrome, hypersensitivity reactions, SEROTONIN SYNDROME
Drug-drug:
Drug-Natural Products:
Lab Test Considerations:
NDC Code