Absorption: 36% absorbed following oral administration.
Distribution: Crosses the placenta; enters breast milk in small amounts.
Protein Binding: 99.4%.
Half-Life: 12 hr.
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | Within 1 hr | 26 hr | 24 hr |
‡Full effects may not be noted for several weeks.
Contraindicated in:
Use Cautiously in:
Neuro: dizziness, fatigue, headache, insomnia, weakness
Resp: cough
CV: hypotension, chest pain, edema
GI: abdominal pain, diarrhea, nausea, vomiting
GU: erectile dysfunction, impaired renal function
Derm: rash
F and E: hyperkalemia
MS: muscle cramps
Resp: dyspnea
Misc: ANGIOEDEMA
Drug-drug:
Lab Test Considerations:
NDC Code