Risk of irritation ↑ by other topical skin-care products (aftershave, cover-up, make-up, perfumes, colognes).
Route/Dosage⬆⬇
(Adults and Children ≥12 yr): Apply once daily at bedtime.
Availability⬆⬇
(Generic available)
Cream: 0.1%
Gel: 0.1%; 0.3% OTC
Solution: 0.1%
Assessment⬆⬇
Assess skin prior to and periodically during therapy. Transient worsening of acne may occur at initiation of therapy. Note degree of skin dryness, erythema, and itching. Usually occur during first 2–4 wk of therapy. May need to reduce frequency or discontinue therapy.
Implementation⬆⬇
Topical Cleanse area with mild or soapless cleanser before applying medication. Apply thin film of cream to areas where acne lesions appear, once daily at nighttime. A mild transitory sensation of warmth or slight stinging may occur shortly after application. Avoid contact with the eyes, lips, angles of the nose, and mucous membranes. Do not apply to cuts, abrasions, eczematous or sunburned skin. May use moisturizers but avoid products containing alpha hydroxy or glycolic acid. Avoid waxing skin in treated area.
Patient/Family Teaching⬆⬇
Instruct patient on correct technique for application of cream.
Explain to patient that a temporary worsening of acne may occur at beginning of therapy.
Caution patient to use sunscreen and protective clothing to prevent photosensitivity reactions. Health care professional should be consulted about sunscreen, as some sunscreens may worsen acne.
Rep: Advise female patients to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Evaluation/Desired Outcomes⬆⬇
Reduction in inflammatory and noninflammatory acne lesions.
