section name header

Pronunciation ⬇

a-DEN-oh-seen

Classifications ⬆ ⬇

Therapeutic Classification: antiarrhythmics

Indications ⬆ ⬇

REMS

Action ⬆ ⬇

  • Restores normal sinus rhythm by interrupting re-entrant pathways in the AV node.
  • Slows conduction time through the AV node.
  • Also produces coronary artery vasodilation.
Therapeutic effects:
  • Restoration of normal sinus rhythm.

Pharmacokinetics ⬆ ⬇

Absorption: IV administration results in complete bioavailability.

Distribution: Taken up by erythrocytes and vascular endothelium.

Metabolism/Excretion: Rapidly converted to inosine and adenosine monophosphate.

Half-Life: <10 sec.

Time/Action Profile ⬆ ⬇

(antiarrhythmic effect)

ROUTEONSETPEAKDURATION
IVimmediateunknown1–2 min



Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: arrhythmias, chest pain, hypotension, MI, palpitations, VENTRICULAR TACHYCARDIA

Derm: facial flushing, burning sensation, sweating

EENT: blurred vision, throat tightness

GI: metallic taste, nausea

MS: neck and back pain

Neuro: apprehension, dizziness, head pressure, headache, lightheadedness., numbness, SEIZURES (ONLY WHEN USED FOR DIAGNOSTIC USE), STROKE (ONLY WHEN USED FOR DIAGNOSTIC USE), tingling

Resp: shortness of breath, chest pressure, hyperventilation

Misc: heaviness in arms, HYPERSENSITIVITY REACTIONS, pressure sensation in groin

Interactions ⬆ ⬇

Drug-drug:

Route/Dosage ⬆ ⬇

Availability ⬆ ⬇

(Generic available)

Assessment ⬆ ⬇

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Adenocard, Adenoscan

Code ⬆

NDC Code