Therapeutic Classification: allergy, cold and cough remedies, antihistamines, antitussives
BEERS REMS
Absorption: Well absorbed after oral or IM administration but 4060% of an oral dose reaches systemic circulation due to first-pass metabolism.
Distribution: Widely distributed. Crosses the placenta; enters breast milk.
Half-Life: 2.47 hr.
(antihistaminic effects)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | 1560 min | 24 hr | 48 hr |
IM | 2030 min | 24 hr | 48 hr |
IV | rapid | unknown | 48 hr |
Contraindicated in:
Use Cautiously in:
CV: hypotension, palpitations
Derm: photosensitivity
EENT: blurred vision, tinnitus
GI: anorexia, dry mouth, constipation, nausea
GU: dysuria, urinary frequency, urinary retention
Local: pain at IM site
Neuro: drowsiness, dizziness, headache, paradoxical excitation (↑ in children)
Resp: chest tightness, thickened bronchial secretions, wheezing
Drug-drug:
Drug-Natural Products:
Lab Test Considerations:
IV Administration:
NDC Code