olive

Therapeutic Classification: antihypertensives, cardioprotective agents, laxatives

Indications ⬆ ⬇

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS

Constipation.
Cardiovascular disease.
Hyperlipidemia.
Hypertension.

Action ⬆ ⬇

Phenols present in olive oil have antioxidant, vasodilating, and antiplatelet properties. Olive oil also improves endothelial tissue function and decreases LDL cholesterol's contribution to atherogenesis in patients with hypercholesterolemia.

Therapeutic effects:

Decreased BP.
Decreased total cholesterol levels.

Pharmacokinetics ⬆ ⬇

Absorption: Unknown

Distribution: Unknown

Metabolism/Excretion: Unknown

Half-Life: Unknown

Time/Action Profile ⬆ ⬇

	ONSET	PEAK	DURATION
PO	unknown	unknown	unknown

Contraind./Precautions ⬆ ⬇

Contraindicated in:

None.

Use Cautiously in:

Pregnancy and lactation (avoid using in amounts greater than those found in foods)
Diabetes.

Adv. Reactions/Side Effects ⬆ ⬇

Derm: contact dermatitis (topical)

Interactions ⬆ ⬇

Natural-Drug Products:

May have additive hypoglycemic effects with antidiabetic agents.
May have additive hypotensive effects with antihypertensive agents.

Natural-Natural Products:

May have additive hypoglycemic effects with herbs that decrease blood glucose levels includingdevil's claw fenugreekgarlicginsengandpsyllium.
May have additive hypotensive effects with herbs that ↓ BP includingcoenzyme Q-10 fish oilL-argininecat's clawandstinging nettle.

Route/Dosage ⬆ ⬇

PO (Adults ): Constipation: 30 mL of oil; Hypertension: 30–40 grams/day; Hyperlipidemia: 23 grams/day (2 tablespoons); Reduction of risk of first myocardial infarction: 54 grams/day.

Availability ⬆ ⬇

Oil:
Leaf:
Fruit pulp:

Assessment ⬆ ⬇

Constipation: Assess patient for abdominal distention, presence of bowel sounds, and usual pattern of bowel function.
- Assess color, consistency, and amount of stool produced
Hypercholesterolemia: Obtain a diet history, especially with regard to fat consumption.

Lab Test Considerations:

Monitor serum cholesterol levels before and periodically during therapy.

Implementation ⬆ ⬇

PO: Administer as directed.

Patient/Family Teaching ⬆ ⬇

Instruct patient to take as directed.
Advice female patient to avoid taking more than is in normal food intake. Notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Evaluation/Desired Outcomes ⬆ ⬇

Soft, formed bowel movement when used for constipation.
Reduction in serum cholesterol levels.

US Brand Names ⬆ ⬇

Extra Virgin Olive Oil, Monounsaturated Fatty Acid, Omega-9 Fatty Acids

Code ⬆

NDC Code

0268- ALK-Abello, Inc.
- 0268-6185- BLACK OLIVE
  - 0268-6185-06- 5 mL in 1 VIAL, MULTI-DOSE (0268-6185-06)

0268- ALK-Abello, Inc.
- 0268-6185- BLACK OLIVE
  - 0268-6185-10- 10 mL in 1 VIAL (0268-6185-10)

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Pronunciation ⬇

Classifications ⬆ ⬇