Therapeutic Classification: antidepressants
Pharmacologic Classification: selective serotonin reuptake inhibitors ssris
BEERS REMS
Absorption: 80% absorbed after oral administration.
Distribution: Enters breast milk.
Half-Life: 35 hr.
Contraindicated in:
Use Cautiously in:
CV: QT interval prolongation, postural hypotension, tachycardia, TORSADES DE POINTES
Derm: sweating, photosensitivity, pruritus, rash
EENT: abnormal accommodation
Endo: SIADH
F and E: hyponatremia
GI: ↑salivation, abdominal pain, anorexia, diarrhea, dry mouth, dyspepsia, flatulence, nausea, altered taste, vomiting
GU: ↓libido, amenorrhea, delayed/absent orgasm, dysmenorrhea, ejaculatory delay/failure, erectile dysfunction, polyuria
Hemat: BLEEDING
MS: arthralgia, myalgia
Neuro: apathy, confusion, drowsiness, insomnia, tremor, weakness, ↓libido, ↑depression, agitation, amnesia, anxiety, dizziness, fatigue, impaired concentration, migraine headache, NEUROLEPTIC MALIGNANT SYNDROME, paresthesia, SUICIDAL THOUGHTS
Resp: cough
Misc: fever, SEROTONIN SYNDROME, yawning
Drug-drug:
Drug-Natural Products:
Hepatic Impairment
Lab Test Considerations:
NDC Code