Dietary management of osteoarthritis; considered to be a medical food product.
Action⬆⬇
Anti-inflammatory and analgesic properties related to inhibition of prostaglandin synthesis by inhibiting cyclo-oxygenase (not COX-2 selective) and other mediators of inflammation.
Therapeutic effects:
Decreased pain/inflammation associated with osteoarthritis, with improved mobility.
Pharmacokinetics⬆⬇
Absorption: Some intestinal conversion prior to absorption, remainder unknown.
Distribution: Unknown.
Metabolism/Excretion: Mostly metabolized by the liver.
PO (Adults ): 250 mg every 12 hr (up to 250 mg three times daily has been used).
Availability⬆⬇
Capsules: 250 mg
Assessment⬆⬇
Assess pain (note type, location, and intensity), range of motion, degree of swelling, and stiffness in affected joints before and periodically during therapy.
Implementation⬆⬇
PO: Administer flavocoxid twice daily.
Patient/Family Teaching⬆⬇
Instruct patient to take flavocoxid as directed. Do not increase does without consulting health care professional.
Evaluation/Desired Outcomes⬆⬇
Decrease in pain and stiffness, and improved mobility in patients with osteoarthritis.
