Contraindicated in:
Use Cautiously in:
Derm: DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS), STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS.
GI: diarrhea, nausea, ↑ liver enzymes, cholelithiasis, HEPATOTOXICITY, pancreatitis.
GU: ↑ serum creatinine.
MS: myalgia, back pain, MYOPATHY/RHABDOMYOLYSIS.
Neuro: headache.
Resp: INTERSTITIAL LUNG DISEASE.
Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA).
Drug-Drug:
(Generic available)
Hypertriglyceridemia
Renal Impairment
Primary Hypercholesterolemia or Mixed Dyslipidemia
Renal Impairment
Fibricor, TriLipix
Therapeutic Classification: lipid-lowering agents
Pharmacologic Classification: fibric acid derivatives
Absorption: Well absorbed following oral administration.
Distribution: Unknown.
Protein Binding: 99%.
Metabolism/Excretion: Fenofibric acid is the active metabolite of fenofibrate. Fenofibric acid is mostly metabolized by glucuronidation and the metabolites are mostly excreted by the kidneys.
Half-life: 20 hr.
NDC Code*