Contraindicated in:
Use Cautiously in:
GI: constipation, abdominal discomfort, abdominal distention, ACUTE ISCHEMIC COLITIS , flatulence, nausea, GI viral infections, hemorrhoids, regurgitation or reflux, TOXIC MEGACOLON.
Drug-Drug:
Therapeutic Classification: anti irritable bowel syndrome agents
Pharmacologic Classification: five ht3 antagonists
Absorption: 5060% absorbed following oral administration.
Distribution: 6595 L.
Protein Binding: 82% bound to plasma proteins.
Metabolism/Excretion: Extensively metabolized by the liver; 13% excreted unchanged in urine.
Half-life: 1.5 hr.
NDC Code*