ofloxacin

REMS

PO: Treatment of the following infections:
- Acute bacterial exacerbations of chronic bronchitis (should be used only when there are no other alternative treatment options),
- Community-acquired pneumonia (CAP),
- Acute uncomplicated cervical and urethral gonorrhea,
- Nongonococcal urethritis and cervicitis,
- Mixed infections of the urethra and cervix,
- Acute pelvic inflammatory disease,
- Urinary tract infections (should be used for acute uncomplicated cystitis only when there are no other alternative treatment options),
- Prostatitis,
- Uncomplicated skin and skin structure infections.
Otic: Otitis externa or otitis media.

Contraindicated in:

Hypersensitivity (cross-sensitivity within class may exist)
QTc interval prolongation
Uncorrected hypokalemia or hypomagnesemia
Concurrent use of Class IA antiarrhythmics (disopyramide, quinidine, procainamide) or Class III antiarrhythmics (amiodarone, sotalol) (↑risk of QTc interval prolongation and torsade de pointes)
History of myasthenia gravis (may worsen symptoms including muscle weakness and breathing problems)
Lactation: Lactation.

Use Cautiously in:

Known or suspected CNS disorder
Renal impairment (dose reduction recommended if CCr ≤50 mL/min)
Cirrhosis
Concurrent use of corticosteroids (↑ risk of tendinitis/tendon rupture)
Kidney, heart, or lung transplant patients (↑ risk of tendinitis/tendon rupture)
Patients with or at risk for aortic aneurysms
OB: Use during pregnancy only if potential maternal benefit justifies potential fetal risk;.
Pedi: Safety and effectiveness not established in children
Geri: ↑ risk for tendon disorders/rupture, hepatotoxicity, aortic aneurysm/dissection (within 2 mo following discontinuation), and QT interval prolongation.

CV: QT interval prolongation, AORTIC ANEURYSM/DISSECTION, TORSADE DE POINTES.

Derm: photosensitivity, rash, STEVENS-JOHNSON SYNDROME.

Endo: hyperglycemia, hypoglycemia.

GI: diarrhea, nausea, CLOSTRIDIOIDES DIFFICILE-ASSOCIATED DIARRHEA (CDAD), abdominal pain, vomiting.

GU: vaginitis.

MS: arthralgia, myalgia, tendinitis, tendon rupture.

Neuro: agitation, anxiety, confusion, depression, dizziness , ELEVATED INTRACRANIAL PRESSURE (INCLUDING PSEUDOTUMOR CEREBRI), hallucinations, headache, insomnia, nightmares, paranoia, peripheral neuropathy, SEIZURES, SUICIDAL THOUGHTS, toxic psychosis, tremor.

Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS).

Drug-Drug:

Concurrent use ofamiodarone, disopyramide, procainamide, dofetilide, quinidine, or sotalol ↑ risk of potentially dangerous arrhythmias in susceptible individuals (avoid concurrent use).
May ↑ theophylline levels and the risk of toxicity.
Administration with antacids, iron salts, bismuth subsalicylate,sucralfate, and zinc salts ↓ absorption.
May ↑ the effects of warfarin.
Levels and effectiveness may be ↓ by antineoplastic agents.
Cimetidine may interfere with elimination.
Probenecid ↓ renal elimination.
May ↑ risk of nephrotoxicity from cyclosporine.
Concurrent corticosteroid therapy may ↑ risk of tendon rupture.
May ↑ risk of hypoglycemia when used with antidiabetic agents.

Drug-Food:

Absorption is impaired by concurrent enteral feeding (because of metal cations).
Absorption of ofloxacin is ↓ by foods and/or dairy products.

(Generic available)

Tablets: 200 mg; 300 mg; 400 mg;
Otic solution: 0.3%;

Acute Bacterial Exacerbations of Chronic Bronchitis

PO (Adults): 400 mg every 12 hr for 10 days.

Community-Acquired Pneumonia

PO (Adults): 400 mg every 12 hr for 10 days.

Uncomplicated Skin/Skin Structure Infections

PO (Adults): 400 mg every 12 hr for 10 days.

Uncomplicated Urethral and Cervical Gonorrhea

PO (Adults): 400 mg single dose.

Nongonococcal Urethritis/Cervicitis

PO (Adults): 300 mg every 12 hr for 7 days.

Mixed Infection of the Urethra and Cervix

PO (Adults): 300 mg every 12 hr for 7 days.

Acute Pelvic Inflammatory Disease

PO (Adults): 400 mg every 12 hr for 10–14 days.

Urinary Tract Infections

PO (Adults): Uncomplicated cystitis due to E. coli or Klebsiella pneumoniae: 200 mg every 12 hr for 3 days; Uncomplicated cystitis due to Citrobacter diversus, Enterobacter aerogenes, Proteus mirabilis, or Pseudomonas aeruginosa: 200 mg every 12 hr for 7 days; Complicated urinary tract infection: 200 mg every 12 hr for 10 days.

Prostatitis

PO (Adults): 300 mg every 12 hr for 6 wk.

Renal Impairment

PO (Adults): CCr 20–50 mL/min: 100% of the usual dose every 24 hr; CCr <20 mL/min: 50% of the usual dose every 24 hr.
Otic (Adults and Children ≥6 mo): Otitis externa 6 mo to 13 yr: : 5 drops instilled into affected ear once daily for 7 days; Otitis externa ≥13 yr: 10 drops instilled into affected ear once daily for 7 days. Acute otitis media in patients 1–12 yr old with tympanostomy tubes: 5 drops instilled into the affected ear twice daily for 10 days. Chronic suppurative otitis media with perforated tympanic membranes in patients ≥12 yr: 10 drops instilled into the affected ear twice daily for 14 days.

~~Floxin~~, Floxin Otic

Inhibits bacterial DNA synthesis by inhibiting DNA gyrase enzyme.

Therapeutic Effects:

Death of susceptible bacteria.

Spectrum:

Active against gram-positive pathogens including:
- Staphylococcus aureus,
- Staphylococcus epidermidis,
- Streptococcus pyogenes,
- Streptococcus pneumoniae.
Gram-negative spectrum notable for activity against:
- Escherichia coli,
- Klebsiella pneumoniae,
- Enterobacter aerogenes,
- Proteus mirabilis,
- Haemophilus influenzaeNeisseria gonorrhoeae,
- Moraxella catarrhalis.
Additional spectrum includes:
- Chlamydophylia pneumoniae,
- Legionella pneumoniae,
- Mycoplasma pneumoniae.

Therapeutic Classification: anti-infectives

Pharmacologic Classification: Fluoroquinolones

Absorption: Well absorbed (98%) following oral administration.

Distribution: Widely distributed. High tissue and urinary levels are achieved. Appears to cross the placenta; enters breast milk.

Metabolism/Excretion: 70–80% excreted unchanged by the kidneys.

Half-life: 5–7 hr.

(blood levels)

ROUTE	ONSET	PEAK	DURATION
PO	rapid	1–2 hr	12 hr

Instruct patient to take medication as directed at evenly spaced times and to finish drug completely, even if feeling better. Take missed doses as soon as possible, unless almost time for next dose. Do not double doses. Advise patient that sharing of this medication may be dangerous.
Advise patients to notify health care professional immediately if they are taking theophylline.
Encourage patient to maintain a fluid intake of at least 1500–2000 mL/day to prevent crystalluria.
Advise patient that antacids or medications containing calcium, magnesium, aluminum, iron, or zinc will decrease absorption and should not be taken within 4 hr before and 2 hr after taking this medication.
May cause dizziness and drowsiness. Caution patient to avoid driving or other activities requiring alertness until response to medication is known.
Advise patient to notify health care professional of any personal or family history of QTc prolongation or proarrhythmic conditions such as recent hypokalemia, significant bradycardia, or recent myocardial ischemia or if fainting spells or palpitations occur. Patients with this history should not receive ofloxacin.
Caution patient to use sunscreen and protective clothing to prevent phototoxicity reactions during and for 5 days after therapy. Notify health care professional if a sunburn-like reaction or skin eruption occurs.
Advise patient that frequent mouth rinses, good oral hygiene, and sugarless gum or candy may minimize dry mouth.
Instruct patients being treated for gonorrhea that partners also must be treated.
Advise patient to report signs of superinfection (furry overgrowth on the tongue, vaginal itching or discharge, loose or foul-smelling stools).
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Instruct patient to notify health care professional if fever and diarrhea develop, especially if stool contains blood, pus, or mucus. Advise patient not to treat diarrhea without consulting health care professional.
Instruct patient to notify health care professional immediately if rash, jaundice, signs of hypersensitivity, or tendon (shoulder, hand, Achilles, and other) pain, swelling, or inflammation occur. If tendon symptoms occur, avoid exercise and use of the affected area. Increased risk in >65 yrs old, kidney, heart and lung transplant recipients, and patients taking corticosteroids concurrently. Therapy should be discontinued.
Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding.
Otic: Instruct parent in correct administration technique.

NDC Code^*

0404- Henry Schein Inc.
0404-7189- Ofloxacin 0404-7189-01- 1 BOTTLE, DROPPER in 1 CARTON (0404-7189-01) > 10 mL in 1 BOTTLE, DROPPER

11980- Allergan, Inc.
11980-779- OCUFLOX 11980-779-05- 1 BOTTLE, DROPPER in 1 CARTON (11980-779-05) > 5 mL in 1 BOTTLE, DROPPER

13985- MWI
13985-602- Ofloxacin 13985-602-05- 1 BOTTLE, DROPPER in 1 CARTON (13985-602-05) > 5 mL in 1 BOTTLE, DROPPER

13985- MWI
13985-602- Ofloxacin 13985-602-10- 1 BOTTLE, DROPPER in 1 CARTON (13985-602-10) > 10 mL in 1 BOTTLE, DROPPER

17478- Akorn, Inc.
17478-713- Ofloxacin 17478-713-10- 1 BOTTLE, DROPPER in 1 CARTON (17478-713-10) > 5 mL in 1 BOTTLE, DROPPER

17478- Akorn, Inc.
17478-713- Ofloxacin 17478-713-11- 1 BOTTLE, DROPPER in 1 CARTON (17478-713-11) > 10 mL in 1 BOTTLE, DROPPER

24208- Bausch and Lomb Incorporated
24208-410- Ofloxacin 24208-410-05- 1 BOTTLE, DROPPER in 1 CARTON (24208-410-05) > 5 mL in 1 BOTTLE, DROPPER

24208- Bausch and Lomb Incorporated
24208-410- Ofloxacin 24208-410-10- 1 BOTTLE, DROPPER in 1 CARTON (24208-410-10) > 10 mL in 1 BOTTLE, DROPPER

24208- Bausch and Lomb Incorporated
24208-434- Ofloxacin 24208-434-05- 1 BOTTLE, DROPPER in 1 CARTON (24208-434-05) > 5 mL in 1 BOTTLE, DROPPER

24208- Bausch and Lomb Incorporated
24208-434- Ofloxacin 24208-434-10- 1 BOTTLE, DROPPER in 1 CARTON (24208-434-10) > 10 mL in 1 BOTTLE, DROPPER

33261- Aidarex Pharmaceuticals LLC
33261-737- Ofloxacin 33261-737-01- 1 BOTTLE, DROPPER in 1 CARTON (33261-737-01) > 5 mL in 1 BOTTLE, DROPPER

50090- A-S Medication Solutions
50090-0891- Ofloxacin 50090-0891-0- 1 BOTTLE, DROPPER in 1 CARTON (50090-0891-0) > 5 mL in 1 BOTTLE, DROPPER

50090- A-S Medication Solutions
50090-1090- Ofloxacin Otic 50090-1090-0- 5 mL in 1 BOTTLE, DROPPER (50090-1090-0)

50090- A-S Medication Solutions
50090-1346- Ofloxacin 50090-1346-0- 1 BOTTLE, DROPPER in 1 CARTON (50090-1346-0) > 10 mL in 1 BOTTLE, DROPPER

50090- A-S Medication Solutions
50090-1736- Ofloxacin 50090-1736-0- 1 BOTTLE, DROPPER in 1 CARTON (50090-1736-0) > 5 mL in 1 BOTTLE, DROPPER

50383- Hi-Tech Pharmacal Co., Inc.
50383-024- Ofloxacin 50383-024-05- 1 BOTTLE, DROPPER in 1 CARTON (50383-024-05) > 5 mL in 1 BOTTLE, DROPPER

50383- Hi-Tech Pharmacal Co., Inc.
50383-024- Ofloxacin 50383-024-10- 1 BOTTLE, DROPPER in 1 CARTON (50383-024-10) > 10 mL in 1 BOTTLE, DROPPER

50436- Unit Dose Services
50436-0713- Ofloxacin 50436-0713-1- 5 CARTON in 1 BOTTLE, DROPPER (50436-0713-1) > 1 mL in 1 CARTON

50436- Unit Dose Services
50436-6112- Ofloxacin 50436-6112-0- 5 mL in 1 BOTTLE, DROPPER (50436-6112-0)

53002- RPK Pharmaceuticals, Inc.
53002-1324- Ofloxacin 53002-1324-1- 5 mL in 1 BOTTLE, DROPPER (53002-1324-1)

53002- RPK Pharmaceuticals, Inc.
53002-1604- Ofloxacin 53002-1604-1- 5 mL in 1 BOTTLE, DROPPER (53002-1604-1)

53002- RPK Pharmaceuticals, Inc.
53002-2604- Ofloxacin Otic 53002-2604-1- 5 mL in 1 BOTTLE, DROPPER (53002-2604-1)

55111- Dr. Reddy's Laboratories Limited
55111-160- Ofloxacin 55111-160-01- 100 TABLET, COATED in 1 BOTTLE (55111-160-01)

55111- Dr. Reddy's Laboratories Limited
55111-160- Ofloxacin 55111-160-05- 500 TABLET, COATED in 1 BOTTLE (55111-160-05)

55111- Dr. Reddy's Laboratories Limited
55111-160- Ofloxacin 55111-160-30- 30 TABLET, COATED in 1 BOTTLE (55111-160-30)

55111- Dr. Reddy's Laboratories Limited
55111-160- Ofloxacin 55111-160-50- 50 TABLET, COATED in 1 BOTTLE (55111-160-50)

55111- Dr. Reddy's Laboratories Limited
55111-160- Ofloxacin 55111-160-78- 10 BLISTER PACK in 1 CARTON (55111-160-78) > 10 TABLET, COATED in 1 BLISTER PACK (55111-160-79)

55111- Dr. Reddy's Laboratories Limited
55111-161- Ofloxacin 55111-161-01- 100 TABLET, COATED in 1 BOTTLE (55111-161-01)

55111- Dr. Reddy's Laboratories Limited
55111-161- Ofloxacin 55111-161-05- 500 TABLET, COATED in 1 BOTTLE (55111-161-05)

55111- Dr. Reddy's Laboratories Limited
55111-161- Ofloxacin 55111-161-30- 30 TABLET, COATED in 1 BOTTLE (55111-161-30)

55111- Dr. Reddy's Laboratories Limited
55111-161- Ofloxacin 55111-161-50- 50 TABLET, COATED in 1 BOTTLE (55111-161-50)

55111- Dr. Reddy's Laboratories Limited
55111-161- Ofloxacin 55111-161-78- 10 BLISTER PACK in 1 CARTON (55111-161-78) > 10 TABLET, COATED in 1 BLISTER PACK (55111-161-79)

55111- Dr. Reddy's Laboratories Limited
55111-162- Ofloxacin 55111-162-01- 100 TABLET, COATED in 1 BOTTLE (55111-162-01)

55111- Dr. Reddy's Laboratories Limited
55111-162- Ofloxacin 55111-162-05- 500 TABLET, COATED in 1 BOTTLE (55111-162-05)

55111- Dr. Reddy's Laboratories Limited
55111-162- Ofloxacin 55111-162-30- 30 TABLET, COATED in 1 BOTTLE (55111-162-30)

55111- Dr. Reddy's Laboratories Limited
55111-162- Ofloxacin 55111-162-50- 50 TABLET, COATED in 1 BOTTLE (55111-162-50)

55111- Dr. Reddy's Laboratories Limited
55111-162- Ofloxacin 55111-162-78- 10 BLISTER PACK in 1 CARTON (55111-162-78) > 10 TABLET, COATED in 1 BLISTER PACK (55111-162-79)

55700- Lake Erie Medical DBA Quality Care Products LLC
55700-066- Ofloxacin 55700-066-10- 5 mL in 1 BOTTLE, DROPPER (55700-066-10)

59390- Altaire Pharmaceuticals Inc.
59390-140- Ofloxacin ophthalmic 59390-140-05- 5 mL in 1 BOTTLE, DROPPER (59390-140-05)

60505- Apotex Corp.
60505-0363- Ofloxacin Otic 60505-0363-1- 5 mL in 1 BOTTLE, DROPPER (60505-0363-1)

60505- Apotex Corp.
60505-0363- Ofloxacin Otic 60505-0363-2- 10 mL in 1 BOTTLE, DROPPER (60505-0363-2)

60505- Apotex Corp.
60505-0560- Ofloxacin 60505-0560-0- 1 BOTTLE, DROPPER in 1 CARTON (60505-0560-0) > 5 mL in 1 BOTTLE, DROPPER

60505- Apotex Corp.
60505-0560- Ofloxacin 60505-0560-1- 1 BOTTLE, DROPPER in 1 CARTON (60505-0560-1) > 10 mL in 1 BOTTLE, DROPPER

63187- Proficient Rx LP
63187-184- Ofloxacin Otic 63187-184-05- 5 mL in 1 BOTTLE, DROPPER (63187-184-05)

63187- Proficient Rx LP
63187-268- Ofloxacin 63187-268-05- 1 BOTTLE, DROPPER in 1 CARTON (63187-268-05) > 5 mL in 1 BOTTLE, DROPPER

63187- Proficient Rx LP
63187-472- Ofloxacin 63187-472-05- 1 BOTTLE, DROPPER in 1 CARTON (63187-472-05) > 5 mL in 1 BOTTLE, DROPPER

63187- Proficient Rx LP
63187-662- Ofloxacin 63187-662-05- 1 BOTTLE, DROPPER in 1 CARTON (63187-662-05) > 5 mL in 1 BOTTLE, DROPPER

63187- Proficient Rx LP
63187-662- Ofloxacin 63187-662-10- 1 BOTTLE, DROPPER in 1 CARTON (63187-662-10) > 10 mL in 1 BOTTLE, DROPPER

63187- Proficient Rx LP
63187-734- Ofloxacin 63187-734-05- 1 BOTTLE, PLASTIC in 1 CARTON (63187-734-05) > 5 mL in 1 BOTTLE, PLASTIC

63187- Proficient Rx LP
63187-734- Ofloxacin 63187-734-10- 1 BOTTLE, PLASTIC in 1 CARTON (63187-734-10) > 10 mL in 1 BOTTLE, PLASTIC

64980- Rising Pharmaceuticals, Inc.
64980-515- Ofloxacin 64980-515-01- 1 BOTTLE, PLASTIC in 1 CARTON (64980-515-01) > 10 mL in 1 BOTTLE, PLASTIC

64980- Rising Pharmaceuticals, Inc.
64980-515- Ofloxacin 64980-515-05- 1 BOTTLE, PLASTIC in 1 CARTON (64980-515-05) > 5 mL in 1 BOTTLE, PLASTIC

68047- Larken Laboratories, Inc.
68047-713- ofloxacin 68047-713-01- 100 TABLET, FILM COATED in 1 BOTTLE (68047-713-01)

68071- NuCare Pharmaceuticals,Inc.
68071-1588- Ofloxacin Otic 68071-1588-5- 5 mL in 1 BOTTLE (68071-1588-5)

68071- NuCare Pharmaceuticals, Inc.
68071-1607- Ofloxacin 68071-1607-5- 5 mL in 1 BOX (68071-1607-5)

68071- NuCare Pharmaceuticals,Inc.
68071-1630- Ofloxacin Otic 68071-1630-3- 10 mL in 1 BOTTLE (68071-1630-3)

68071- NuCare Pharmaceuticals,Inc.
68071-4055- Ofloxacin 68071-4055-5- 5 mL in 1 BOX (68071-4055-5)

68071- NuCare Pharmaceuticals,Inc.
68071-4832- Ofloxacin 68071-4832-5- 5 mL in 1 BOTTLE (68071-4832-5)

68788- Preferred Pharmaceuticals Inc.
68788-7003- Ofloxacin 68788-7003-5- 1 BOTTLE, DROPPER in 1 CARTON (68788-7003-5) > 5 mL in 1 BOTTLE, DROPPER

68788- Preferred Pharmaceuticals Inc.
68788-8993- Ofloxacin 68788-8993-5- 5 mL in 1 BOTTLE, PLASTIC (68788-8993-5)

70518- REMEDYREPACK INC.
70518-0192- Ofloxacin 70518-0192-0- 1 BOTTLE, DROPPER in 1 CARTON (70518-0192-0) > 5 mL in 1 BOTTLE, DROPPER

70518- REMEDYREPACK INC.
70518-0308- Ofloxacin 70518-0308-0- 1 BOTTLE, DROPPER in 1 CARTON (70518-0308-0) > 10 mL in 1 BOTTLE, DROPPER

70518- REMEDYREPACK INC.
70518-1892- Ofloxacin 70518-1892-0- 1 BOTTLE, PLASTIC in 1 CARTON (70518-1892-0) > 10 mL in 1 BOTTLE, PLASTIC

70518- REMEDYREPACK INC.
70518-2037- Ofloxacin 70518-2037-0- 1 BOTTLE, PLASTIC in 1 CARTON (70518-2037-0) > 5 mL in 1 BOTTLE, PLASTIC

71209- Cadila Pharmaceuticals Limited
71209-097- OFLOXACIN 71209-097-02- 50 TABLET, FILM COATED in 1 BOTTLE (71209-097-02)

71209- Cadila Pharmaceuticals Limited
71209-097- OFLOXACIN 71209-097-05- 100 TABLET, FILM COATED in 1 BOTTLE (71209-097-05)

71209- Cadila Pharmaceuticals Limited
71209-097- OFLOXACIN 71209-097-10- 500 TABLET, FILM COATED in 1 BOTTLE (71209-097-10)

71209- Cadila Pharmaceuticals Limited
71209-098- OFLOXACIN 71209-098-02- 50 TABLET, FILM COATED in 1 BOTTLE (71209-098-02)

71209- Cadila Pharmaceuticals Limited
71209-098- OFLOXACIN 71209-098-05- 100 TABLET, FILM COATED in 1 BOTTLE (71209-098-05)

71209- Cadila Pharmaceuticals Limited
71209-098- OFLOXACIN 71209-098-10- 500 TABLET, FILM COATED in 1 BOTTLE (71209-098-10)

71209- Cadila Pharmaceuticals Limited
71209-099- OFLOXACIN 71209-099-02- 100 TABLET, FILM COATED in 1 BOTTLE (71209-099-02)

71209- Cadila Pharmaceuticals Limited
71209-099- OFLOXACIN 71209-099-05- 500 TABLET, FILM COATED in 1 BOTTLE (71209-099-05)

71209- Cadila Pharmaceuticals Limited
71209-099- OFLOXACIN 71209-099-10- 50 TABLET, FILM COATED in 1 BOTTLE (71209-099-10)

75834- Nivagen Pharmaceuticals, Inc.
75834-112- OFLOXACIN 75834-112-01- 100 TABLET, COATED in 1 BOTTLE (75834-112-01)

75834- Nivagen Pharmaceuticals, Inc.
75834-112- OFLOXACIN 75834-112-05- 500 TABLET, COATED in 1 BOTTLE (75834-112-05)

75834- Nivagen Pharmaceuticals, Inc.
75834-112- OFLOXACIN 75834-112-50- 50 TABLET, COATED in 1 BOTTLE (75834-112-50)

75834- Nivagen Pharmaceuticals, Inc.
75834-119- OFLOXACIN 75834-119-01- 100 TABLET, COATED in 1 BOTTLE (75834-119-01)

75834- Nivagen Pharmaceuticals, Inc.
75834-119- OFLOXACIN 75834-119-05- 500 TABLET, COATED in 1 BOTTLE (75834-119-05)

75834- Nivagen Pharmaceuticals, Inc.
75834-119- OFLOXACIN 75834-119-50- 50 TABLET, COATED in 1 BOTTLE (75834-119-50)

75834- Nivagen Pharmaceuticals, Inc.
75834-120- OFLOXACIN 75834-120-01- 100 TABLET, COATED in 1 BOTTLE (75834-120-01)

75834- Nivagen Pharmaceuticals, Inc.
75834-120- OFLOXACIN 75834-120-05- 500 TABLET, COATED in 1 BOTTLE (75834-120-05)

75834- Nivagen Pharmaceuticals, Inc.
75834-120- OFLOXACIN 75834-120-50- 50 TABLET, COATED in 1 BOTTLE (75834-120-50)

75834- Nivagen Pharmaceuticals, Inc.
75834-199- OFLOXACIN 75834-199-01- 100 TABLET, COATED in 1 BOTTLE (75834-199-01)

75834- Nivagen Pharmaceuticals, Inc.
75834-199- OFLOXACIN 75834-199-05- 500 TABLET, COATED in 1 BOTTLE (75834-199-05)

75834- Nivagen Pharmaceuticals, Inc.
75834-199- OFLOXACIN 75834-199-50- 50 TABLET, COATED in 1 BOTTLE (75834-199-50)

75834- Nivagen Pharmaceuticals, Inc.
75834-200- OFLOXACIN 75834-200-01- 100 TABLET, COATED in 1 BOTTLE (75834-200-01)

75834- Nivagen Pharmaceuticals, Inc.
75834-200- OFLOXACIN 75834-200-05- 500 TABLET, COATED in 1 BOTTLE (75834-200-05)

75834- Nivagen Pharmaceuticals, Inc.
75834-200- OFLOXACIN 75834-200-50- 50 TABLET, COATED in 1 BOTTLE (75834-200-50)

75834- Nivagen Pharmaceuticals, Inc.
75834-201- OFLOXACIN 75834-201-01- 100 TABLET, COATED in 1 BOTTLE (75834-201-01)

75834- Nivagen Pharmaceuticals, Inc.
75834-201- OFLOXACIN 75834-201-05- 500 TABLET, COATED in 1 BOTTLE (75834-201-05)

75834- Nivagen Pharmaceuticals, Inc.
75834-201- OFLOXACIN 75834-201-50- 50 TABLET, COATED in 1 BOTTLE (75834-201-50)

section name header

Indications ⬇

Contraind./Precautions ⬆ ⬇

Adv. Reactions/Side Effects ⬆ ⬇

Interactions ⬆ ⬇

Availability ⬆ ⬇

Route/Dosage ⬆ ⬇

US Brand Names ⬆ ⬇

Action ⬆ ⬇

Classifications ⬆ ⬇

Pharmacokinetics ⬆ ⬇

Time/Action Profile ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

Code ⬆