section name header

Indications ⬇

REMS

Betapace AF and Sotylize:

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: ARRHYTHMIAS, BRADYCARDIA, HF, PULMONARY EDEMA, orthostatic hypotension, peripheral vasoconstriction.

Derm: itching, rash.

EENT: blurred vision, dry eyes, nasal stuffiness.

Endo: hyperglycemia, hypoglycemia.

GI: constipation, diarrhea, nausea.

GU: erectile dysfunction, ↓ libido.

MS: arthralgia, back pain, muscle cramps.

Neuro: fatigue, weakness, anxiety, dizziness, drowsiness, insomnia, memory loss, mental depression, mental status changes, nervousness, nightmares, paresthesia.

Resp: bronchospasm, wheezing.

Misc: drug-induced lupus syndrome.

Interactions ⬆ ⬇

Drug-Drug:

Availability ⬆ ⬇

(Generic available)

Route/Dosage ⬆ ⬇

Ventricular Arrhythmias

Renal Impairment

Atrial Fibrillation/Atrial Flutter

Renal Impairment

US Brand Names ⬆ ⬇

Betapace, Betapace AF, Sorine, Sotylize

Action ⬆ ⬇

Therapeutic Effects:

Classifications ⬆ ⬇

Therapeutic Classification: antiarrhythmics (class III)

Pharmacokinetics ⬆ ⬇

Absorption: Well absorbed following oral administration (bioavailability 90–100%).

Distribution: Crosses the placenta; enters breast milk.

Metabolism/Excretion: Elimination is mostly renal.

Half-life: 12 hr (↑ in renal impairment).

Canadian Brand Names ⬆ ⬇

Rylosol

Time/Action Profile ⬆ ⬇

(antiarrhythmic effects)

ROUTEONSETPEAKDURATION
POhr2–3 days8–12 hr

Patient/Family Teaching ⬆ ⬇

Pronunciation ⬆ ⬇

SOE-ta-lole audio

Code ⬆

NDC Code*