Contraindicated in:
Use Cautiously in:
EENT: deepening of voice.
CV: MI, STROKE, VENOUS THROMBOEMBOLISM, edema.
GI: cholestatic jaundice, drug-induced hepatitis, liver function test elevation, nausea, vomiting.
GU: change in libido, erectile dysfunction, priapism, prostatic enlargement.
Endo: gynecomastia, hirsutism, oligospermia, hypercholesterolemia.
F and E: hypercalcemia, hyperkalemia, hyperphosphatemia.
Derm: male pattern baldness.
Local: pain at implantation site.
Drug-Drug:
Male Hypogonadism (replacement therapy)
Delayed Male Puberty
Absorption: Pellets slowly release testosterone.
Distribution: Crosses the placenta.
Protein Binding: 98%.
Metabolism/Excretion: Metabolized by the liver; 90% eliminated in urine as metabolites.
Half-life: 10100 min.
(androgenic effects)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
SC | unknown | unknown | 36 mo |
Response is highly variable among individuals; may take mo.
NDC Code*