nye-tro-GLI-ser-in 
Contraindicated in:
Use Cautiously in:
CV: hypotension, tachycardia, syncope.
Derm: contact dermatitis (transdermal), flushing.
EENT: blurred vision.
GI: abdominal pain, nausea, vomiting.
Neuro: dizziness, headache, apprehension, restlessness, weakness.
Misc: alcohol intoxication (large IV doses only), tolerance.
Drug-Drug:
(Generic available)
nitroglycerin extended-release capsules: Nitro-Time
nitroglycerin intravenous: Nitro-Bid IVTridil
nitroglycerin sublingual tablets: Nitrostat
Nitroglycerin Transdermal Ointment: Nitro-Bid
nitroglycerin transdermal patch: Nitro-Dur
nitroglycerin translingual spray: Nitrolingual, Nitromist
Absorption: Well absorbed after oral, buccal, and sublingual administration. Also absorbed through skin. Orally administered nitroglycerin is rapidly metabolized, leading to ↓ bioavailability.
Distribution: Unknown.
Metabolism/Excretion: Undergoes rapid and almost complete metabolism by the liver; also metabolized by enzymes in bloodstream.
Half-life: 1–4 min.
nitroglycerin intravenous: Nitroject
nitroglycerin transdermal patch: Trinipatch
nitroglycerin translingual spray: Rho-Nitro
(cardiovascular effects)
| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| SL/Translingual | 1–3 min | unknown | 30–60 min |
| PO-ER | 40–60 min | unknown | 8–12 hr |
| Oint | 20–60 min | unknown | 4–8 hr |
| Patch | 40–60 min | unknown | 8–24 hr |
| IV | immediate | unknown | several min |
NDC Code*